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Faculty Profile

Jason EriksenJason Eriksen

Associate Professor of Pharmacology
Department of Pharmacological and Pharmaceutical Sciences
Affiliate Member, UH Center for Nuclear Receptors

Office: Health 2
University of Houston College of Pharmacy
4849 Calhoun, Room 5021
Houston, TX 77204-5037

Contact: jeriksen@central.uh.edu - 713-743-1226 - Fax: 713-743-1884

Research:

Dementia is a chronic or persistent disorder of the mental processes caused by brain disease or injury and marked by memory disorders, personality changes, and impaired reasoning. Alzheimer's disease is the most common form of dementia. Dr. Eriksen's research interests are centered around the discovery of basic mechanisms and translational research for Alzheimer's disease and other forms of dementia.

  • B.S., Biology and English, Wake Forest University, Winston-Salem, NC
  • Ph.D., Neuroscience, Loyola University Chicago, Chicago, IL
  • Postdoctoral fellow, The Mayo Clinic, Jacksonville, FL

Google Scholar Profile
  • Guo J, Artur C, Womack T, Eriksen JL, Mayerich D. Multiplex protein-specific microscopy with ultraviolet surface excitation. Biomed Opt Express. 2019 Dec 6;11(1):99-108. doi: 10.1364/BOE.11.000099. PMID: 32010503; PMCID: PMC6968765.
  • Guo J, Artur C, Eriksen JL, Mayerich D. Three-Dimensional Microscopy by Milling with Ultraviolet Excitation. Sci Rep. 2019 Oct 10;9(1):14578. doi:10.1038/s41598-019-50870-1. PMID: 31601843; PMCID: PMC6787072.
  • Tanifum EA, Ghaghada K, Vollert C, Head E, Eriksen JL, Annapragada A.J A Novel Liposomal Nanoparticle for the Imaging of Amyloid Plaque by Magnetic Resonance Imaging.Alzheimers Dis. 2016;52(2):731-45. doi: 10.3233/JAD-151124. PMID: 27031484
  • Vollert CT, Moree WJ, Gregory S, Bark SJ, Eriksen JL. Sci Rep. 2015 Nov 27;5:17322. Formaldehyde scavengers function as novel antigen retrieval agents. doi: 10.1038/srep17322. PMID: 26612041
  • Ohia-Nwoko O; Montazari S; Lau YS; Eriksen J.L. Long-term treadmill exercise attenuates tau pathology in P301S tau transgenic mice. Mol Neurodegener. 2014 Nov 28;9(1):54. PMID: 25432085
  • Vollert, C.; Ohia, O.; Akasaka, H.; Berridge, C.; Ruan, K-H.; Eriksen, J. L., Prostacyclin synthase-overexpression in mice impacts memory and anxiety-like behavior. Behavioural Brain Research 2013 Oct 16. pii: S0166-4328(13)00620-7. doi: 10.1016/j.bbr.2013.10.012. PMID: 24140503.
  • Hoshino, A.; Helwig, M.; Rezaei, S.; Berridge, C.; Eriksen, J. L.; Lindberg, I., A Novel Function for proSAAS as an amyloid anti-aggregant in Alzheimer's disease. J Neurochem 2013, Sep 17. doi: 10.1111/jnc.12454. PMID: 24102330.
  • Hazra, A.; Gu, F.; Aulakh, A.; Berridge, C.; Eriksen, J. L.; Ziburkus, J., Inhibitory neuron and hippocampal circuit dysfunction in an aged mouse model of Alzheimer's disease. PLoS One 2013, May 17;8(5):e64318. doi: 10.1371/journal.pone.0064318. Print 2013. PMID: 23691195. Corresponding authors.
  • Rademakers, R.; Eriksen, J. L.; Baker, M.; Robinson, T.; Ahmed, Z.; Lincoln, S. J.; Finch, N.; Rutherford, N. J.; Crook, R. J.; Josephs, K. A.; Boeve, B. F.; Knopman, D. S.; Petersen, R. C.; Parisi, J. E.; Caselli, R. J.; Wszolek, Z. K.; Uitti, R. J.; Feldman, H.; Hutton, M. L.; Mackenzie, I. R.; Graff-Radford, N. R.; Dickson, D. W., Common variation in the miR-659 binding-site of GRN is a major risk factor for TDP43-positive frontotemporal dementia. Hum Mol Genet 2008, 17 (23), 3631-42. doi: 10.1093/hmg/ddn257. Epub 2008 Aug 21. PMID: 18723524.
  • Kukar, T. L.; Ladd, T. B.; Bann, M. A.; Fraering, P. C.; Narlawar, R.; Maharvi, G. M.; Healy, B.; Chapman, R.; Welzel, A. T.; Price, R. W.; Moore, B.; Rangachari, V.; Cusack, B.; Eriksen, J.; Jansen-West, K.; Verbeeck, C.; Yager, D.; Eckman, C.; Ye, W.; Sagi, S.; Cottrell, B. A.; Torpey, J.; Rosenberry, T. L.; Fauq, A.; Wolfe, M. S.; Schmidt, B.; Walsh, D. M.; Koo, E. H.; Golde, T. E., Substrate-targeting gamma-secretase modulators. Nature 2008, 453 (7197), 925-9. doi: 10.1038/nature07055. PMID: 18548070.
  • Baker, M.; Mackenzie, I. R.; Pickering-Brown, S. M.; Gass, J.; Rademakers, R.; Lindholm, C.; Snowden, J.; Adamson, J.; Sadovnick, A. D.; Rollinson, S.; Cannon, A.; Dwosh, E.; Neary, D.; Melquist, S.; Richardson, A.; Dickson, D.; Berger, Z.; Eriksen, J.; Robinson, T.; Zehr, C.; Dickey, C. A.; Crook, R.; McGowan, E.; Mann, D.; Boeve, B.; Feldman, H.; Hutton, M., Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17. Nature 2006, 442 (7105), 916-9. Epub 2006 Jul 16. PMID: 16862116.
  • Weggen, S.; Eriksen, J. L.; Das, P.; Sagi, S. A.; Wang, R.; Pietrzik, C. U.; Findlay, K. A.; Smith, T. E.; Murphy, M. P.; Bulter, T.; Kang, D. E.; Marquez-Sterling, N.; Golde, T. E.; Koo, E. H., A subset of NSAIDs lower amyloidogenic Abeta42 independently of cyclooxygenase activity. Nature 2001, 414 (6860), 212-6. (Cover story; ** Milestone paper, Alzheimer Research Forum.) PMID: 11700559.

Honors

  • National Academy of Inventors, Senior Member, 2020 - Present
  • University of Houston, Excellence in Research, 2014

Professional Certifications and Licenses

  • PMI Agile Certified Practitioner, 2020 - Present
  • Project Management Professional, 2017 - Present