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  4. Fanfei Meng

College of Pharmacy

Faculty Profile

mengFanfei Meng, Ph.D.

Assistant Professor of Pharmaceutics
Department of Pharmacological and Pharmaceutical Sciences

Office: 
University of Houston College of Pharmacy
Health 2, Room 7045
4349 Martin Luther King Boulevard
Houston, TX 77204-5037

Contact: fmeng6@central.uh.edu 

Lab: https://www.menglab.site/

Research:

The research focus of the Meng lab is at the interface of drug delivery, pharmaceutical sciences, nanotechnology, biomedical engineering, material science, immunology, and microbiology. The lab is particularly interested in engineering new drug delivery systems to deliver biomacromolecules such as proteins and nucleic acids that modulate immune functions to fight cancer, autoimmune, infectious, and inflammatory diseases.
  • Ph.D., China Pharmaceutical University 2014 - 2015
  • Joint Ph.D., Purdue University 2015 - 2018 

Google Scholar Profile
  • Nguyen Cao, T.G., and Meng, F*., 2025. Unleashing the power of nucleic acid therapeutics through efficient cytosolic delivery. Journal of Controlled Release, p.113774. (*Corresponding author)
  • Truong Hoang, Q., and Meng, F*., 2025. Unlocking the Full Therapeutic Potential of Lipid Nanoparticles Through Extrahepatic Delivery. Nano Research, 18 (5). (*Corresponding author)
  • Meng, F., He, Y., Wang, J., Parra, K.G., Zhao, J., Yuan, Z., Fishel, M. L., Ratliff, T.L. and Yeo, Y., 2025. Timed delivery of innate immune activation and checkpoint blockade by immunoactive nanocomplexes overcomes the resistance of an immune-cold tumor. Journal of Controlled Release, 381, p.113579.
  • Kafle, U., Truong Hoang, Q., Nguyen Cao, T.G., and Meng, F*., 2024. Development of Thermally Stable LNP/mRNA Delivery Systems: Current Progress and Future Prospects. Molecular Pharmaceutics. (*Corresponding author)
  • Meng, F., Wang, J, He, Y., Creswell, G.M., Lanman, N.A., Lyle, L.T., Ratliff, T.L., Yeo, Y., 2022. A single local delivery of paclitaxel and nucleic acids via an immunoactive polymer eliminates solid tumors and induces systemic antitumor immunity. Proceedings of the National Academy of Sciences, 119(22), p.e2122595119.
  • Meng, F., Wang, J., and Yeo, Y., 2022. Nucleic acid and oligonucleotide delivery for activating innate immunity in cancer immunotherapy. Journal of Controlled Release, 345, 586-600.
  • Meng, F.* Kwon, S*, Wang, J*, Yeo, Y. 2020. Immunoactive drug carriers in cancer therapy. In Biomaterials for Cancer Therapeutics (pp. 53-94). Woodhead Publishing. (* Co-first author)
  • Wang, J.*, Meng, F.*, Kim, B.K., Ke, X. and Yeo, Y., 2019. In-vitro and in-vivo difference in gene delivery by lithocholic acid-polyethyleneimine conjugate. Biomaterials, 119296. (* co-first author)
  • Meng, F., Wang, J., Ping, Q. and Yeo, Y., 2019. Camouflaging nanoparticles for ratiometric delivery of therapeutic combinations. Nano Letters, 19(3), 1479-1487.
  • Meng, F., Wang, J., Ping, Q. and Yeo, Y., 2018. Quantitative assessment of nanoparticle biodistribution by fluorescence imaging, revisited. ACS Nano, 12(7), 6458-6468.
  • Meng, F*., Han, N*., and Yeo, Y., 2017. Organic nanoparticle systems for spatiotemporal control of multimodal chemotherapy. Expert Opinion on Drug Delivery, 14(3), 427-446. (* co-first author)
  • Meng, F., Asghar, S., Xu, Y., Wang, J., Jin, X., Wang, Z., Wang, J., Ping, Q., Zhou, J. and Xiao, Y., 2016. Design and evaluation of lipoprotein resembling curcumin-encapsulated protein-free nanostructured lipid carrier for brain targeting. International Journal of Pharmaceutics, 506(1-2), 46-56.
  • Meng, F., Asghar, S., Gao, S., Su, Z., Song, J., Huo, M., Meng, W., Ping, Q. and Xiao, Y., 2015. A novel LDL-mimic nanocarrier for the targeted delivery of curcumin into the brain to treat Alzheimer's disease. Colloids and Surfaces B: Biointerfaces, 134, 88-97.
  • Wang, J., Meng, F., and Yeo, Y., 2024. Delivery of STING agonists for cancer immunotherapy. Current Opinion in Biotechnology, 87, p.103105.
  • Kwon, S., Meng, F., Tamam, H., Gadalla, H.H., Wang, J., Dong, B., Hopf-Jannasch, A.S., Ratliff, T.L., Yeo, Y., 2024. Systemic delivery of paclitaxel by find-me nanoparticles activates anti-tumor immunity and eliminates tumors. ACS Nano, 18(4), pp.3681-3698.
  • Controlled Release Society Annual Meeting, Best Poster Winner, 2023
  • Purdue University Center for Cancer Research Post Doc Travel Award, 2022-23
  • American Association of Gene and Cell Therapy (ASGCT) Travel Award, 2023
  • American Association of Pharmaceutical Scientists (AAPS) Best Abstract Award, 2022
  • Purdue Postdoctoral Travel Award by Purdue Graduate School, 2022
  • Graduate School Mentoring Award for Postdoctoral Trainees, 2021