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AI Research
at UH

Discover our cutting-edge research initiatives that are pushing the boundaries of artificial intelligence across multiple disciplines and applications.

 

Major Research Initiatives

Analysis Capabilities for Competition, Crisis, and Conflict (AC4)

Principal Investigator:  Craig Glennie,  $63.5M - U.S. Army 

AI-FEED: Connecting Food Charities to End Hunger

Principal Investigator: Ioannis Kakadiaris

 

AI-SERVE: Emergency Food Distribution

Principal Investigator: Ioannis Kakadiaris

Examining Human Trust in AI-Generated Intelligence Analysis

Principal Investigator:  Zachary Zwald, $1.6M - U.S. Army DEVCOM DAC

Community Responsive Algorithms for Social Accountability

Co-Investigator: Lydia Tiede,  $749,857 - National Science Foundation

AI-Doctor Collaborative Medical Image Diagnosis

Principal Investigator: Zhigang Deng,  A computational framework for AI to collaborate with human radiologists on medical diagnosis tasks

 

Research by Domain

Healthcare & Medical AI

AI for Lupus Nephritis Diagnosis

Principal Investigators: Chandra Mohan, Hugh Roy and Lillie Cranz Cullen Endowed

Cancer Fighting Software Development

Principal Investigator:  Badrinath Roysam

AI System for Diabetes Complications Prediction

Principal Investigator:  Dr. Winston Liaw

Radiology Training Enhancement

Principal Investigator:  Van Nguyen


Engineering & Infrastructure

Digital Bridge Safety Monitoring

Principal Investigator: Vedhus Hoskere

Energy Infrastructure Maintenance

Principal Investigator: Vedhus Hoskere

Underground Power Line Installation

Principal Investigator: Jiefu Chen

Wind Forecasting in Urban Areas

Principal Investigator: Mostafa Momen


Computer Science

Detection of Trojans in Large Language Models

Principal Investigator: Amin Alipour

Machine Learning for Cyberattack Prediction

Investigators: Rakesh Verma, Gopal Pandurangan

Data Centric AI for Seismic Analysis

Principal Investigator: Shishir Shah

 


Mathematics

Geometric Deep Learning

Principal Investigator: Nicolas Charon

Transfer Learning for Dynamical Systems

Investigators: Ilya Timofeyev, William Ott

Data-Driven Reduced Order Models

Investigators: Annalisa Quaini, Min Wang

Machine Learning and Geometric Descriptors

Principal Investigator: Demetrio Labate


College of  Optometry

Establishment of Health Data Landing Zone for Clinical Informatics and AI Research

Investigators: Michael Twa, Rene Enriquez
Funding: College IDC

SmartPrep: AI-Driven Tools for Optometry Board Exam Success

Investigators: Lan Chi Nguyen, Kimberly Lambreghts,  and Anita Ticak
Funding: Provost AI Pilot Grant

Large-Scale Classification of Retinal Synapses

Investigators: Luca Della Santina, PhD, PharmD
 Funding: UHCO Research excellence, and NIH/NEI U24 (in collaboration with Indiana University, UCSF, and OHSU)

Automatic Identification of Ocular Diseases from Face Photographs

Investigators: Luca Della Santina, PhD, PharmD
 Funding: UHCO Research excellence (Eyemeter), and NIH/NEI R21 EY032567 (TrachomaFinder)

Evaluating ChatGPT-4 for Diagnosing Visual Disorders in Primary Eye Care

Investigators: Tarsis Gesteira Ferreira, PhD
Funding source: NIH/NEI T35EY007088

(DRUG Development) Use of AI-Based Protein Design

Investigators: Nimesh B Patel, OD, PhD
 Funding source: NIH/NEI EY 036014

 Deep Learning Method: Segmentation of OCT Images of Retinal Layers & of Major Vasculature

Investigators: Kaitlyn Sapoznik, OD, PhD
 Funding source: NIH/NEI EY033743 and EY029229

 

Development of Deep Learning Based Methods for Segmenting Retinal Vasculature in Adaptive Optics Scanning Laser Ophthalmoscope (AOSLO) Images

Investigators: Diane Sayah OD, PhD
Funding source: NIH Consortium for Translational & Precision Health (CTPH) K12 (Baylor/UH)

Neural Network Approach to Segmentation of Vascular Choroid of the Eye

 Investigators: Diane Sayah OD, PhD
 Funding Source: UH start-up, and American Academy of Optometry

 

 

Research Centers and Institutes

 

 

Publications

 

Artificial Intelligence, Legal Change, and Separation of Power

88 CINN. L. REV. 1083 (2020)
Andrew C. Michael

Self-Interest and Preferences for the Regulation of Artificial Intelligence

Journal of Information Technology & Politics 22(3), 2025
Tobias Heinrich and Christopher Witko.

Effective Implementation of Predictive Sales Analytics

Journal of Marketing Research, 61 (4), 718-741.
Habel, Johannes, Sascha Alavi, and Nicolas Heinitz (2024)

Exploring Traffic Simulation and Cybersecurity Strategies Using LLMs

In 2025 IEEE Security and Privacy Workshops (SPW) (pp. 346-351). IEEE.
Gao, L., Liu, Y., Chen, H., Liu, D., Zhang, Y., & Sun, J. (2025)

Between Code and Culture: The Evolving Role of Conversation Designers and UX in AI Development

Science, Technology, & Human Values (2025)
Elizabeth Rodwell

Media Frames, AI Romantic Relationships, and the Perspectives of People in Relationships; Mapping and Comparing News Media Themes with User Perspectives

Information, Communication, & Society (2024)
Liao, Tony, Elizabeth Rodwell, and Debriunna Porter

Hyped but Invisible: Good UX and Good Gender Practices in and out of the Conversal AI Sandbox

Practicing Anthropology (2024)
Elizabeth Rodwell

Implications of bias in automated writing quality scores for fair and equitable assessment decisions

School Psychology (2023)
Matta, M., Mercer, S. H., & Keller-Margulis, M. A.

Cost Analysis of two approaches to writing screening

Journal of School Psychology (2022)
Matta, M., Keller-Margulis, M.A., Mercer, S.H.

Evaluating validity and bias for hand-calculated and automated written expression curriculum-based measurement scores

Assessment in Education: Principles, Policy & Practice (2022)
Matta, M., Mercer, S.H., Keller-Margulis, M.A.

Validity of Automated Text Evaluation: A Comparison Study

Reading and Writing: An Interdisciplinary Journal (2021)
Keller-Margulis, M.A., Mercer, S.H., & Matta, M.

AI-FEED: Prototyping an AI powered platform for the food charity ecosystem

International Journal of Computational Intelligence Systems (2024)
Sammer, M., Seong, K. Olvera, N., Gronseth, S., Anderson-Fletcher, E., Jiao, J., Reese, A., & Kakadiaris, I. A. 

 

Selected Awards & Grants

 

The AI-Driven Culturally Responsive Cognitive and Communication Intervention for Hispanic and Chinese-American Bilingual Autistic Children

Minority Health Grant Program/THECB. $400,000.
Investigator: Miao Li

Discovering AI Arts Workshop

ARTS Connect Houston. $3,500.
Investigator: Sheng Kuan Chung 

Identifying Optimal Prompt Type and Scoring Metrics for Written Expression Curriculum-Based Measurement

Institute of Education Sciences. $1,387,725.
Investigator: Milena Keller-Margulis

AI-Assisted Learning

Leonora “Lora” Kaldaras was named a 2025 National Academy of Education/Spencer Postdoctoral Fellow for her work on AI-assisted learning. 

Designing Conversational AI Systems

National Science Foundation
10/1/2025-9/30/2028. $267,443.
Investigator: Elizabeth Rodwell

AI Reasoning and Code Generation

Sui Foundation’s Academic Research Award
Google Cloud Research Innovators Program
Investigator: Rabimba Karanjai
Read more

AI-Enhanced Oil Spill Detection

Integrating Hyperspectral Sensing and Molecular Fingerprinting; Funding agency 
(UH DoR; Amount: $10,000; Grant period: 09/01/2024-12/31/2025;
Investigators: Jagos Radovic, Co-PIs: Shuhab Khan, Jiajia Sun)

Community Responsive Algorithms for Social Accountability

(2021-2024), $749,857
Co-Investigator (with Ryan Kennedy, Ioannis Kakadiaris, and Andrew Michaels
Investigator: Lydia Tiede, National Science Foundation Grant, award CCF 2131504

Integrating Artificial Intelligence Literacy into Athletic Training Education

 Selected as the recipient of the 2025 Innovation Award, CAATE Foundation
Investigators: Ashlyne Elliott, PhD, LAT, ATC, Layci Harrison, PhD, LAT, ATC 

Analysis Capabilities for Competition, Crisis, and Conflict (AC4)

$63.5M.
Investigator:  Craig Glennie, Army

Characterizing Expected Uncertainty in Spaceborne High-Resolution Terrain Models for Examining Surface Processes

$505k
Investigator: Craig Glennie, NASA

HYDROPOWER RESERVOIR MODELING POWERED BY DEEP REINFORCEMENT LEARNING

Funding agency Deptarment of Energy
Investigator: Hongyi Li

Health behavior counseling using multi-modal large language models in pursuit of health equity for minoritized populations.

NIH AIM-AHEAD Consortium Development Program Innovation for Equity Call for Proposals.
OT2OD032581. 10/1/2024-9/30/2025. $499,992.
Role: Principal Investigator Winston Liaw

Artificial Intelligence/Machine Learning Student/Resident Curriculum and Video Series for Front-Line Clinicians

Gordon and Betty Moore Foundation
0/1/2023 – 6/1/2025. $102,500.
Role: Principal Investigator Winston Liaw

 

Teaching Innovation Program Grant - AI Awardees