Dr. Michael Nikolaou, Professor of Chemical and Biomolecular Engineering

Cullen College of Engineering, Department of Chemical and Biomolecular Engineering

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• Areas of expertise

  • Computer Aided Systems Engineering
  • Oil and gas production systems
  • Semiconductor manufacturing tools and processes
  • Effective development and use of antibiotics

• Awards

  • Cullen College of Engineering Alumni Awards, Abraham E. Dukler Distinguished Engineering Faculty Award, 2017
  • Senior Faculty Research Award, 2010
  • AIChE CAST Director, 2015-2017

  More information in research website above.

• Publications

  • Michael Nikolaou, Computer-aided process engineering in oil and gas production, In Computers & Chemical Engineering, Volume 51, 2013, Pages 96-101, ISSN 0098-1354. Link
    Keywords: Oil and gas; Managed pressure drilling (MPD); Shale gas; Natural gas; Unconventional resources
  • Breyholtz, O.; Nygaard, G.; Nikolaou, M., Managed-Pressure Drilling: Using Model Predictive Control To Improve Pressure Control During Dual-Gradient Drilling. Spe Drilling & Completion 2011, 26 (2), 182-197., 2011
  • Darby, M. L.; Nikolaou, M.; Jones, J.; Nicholson, D., RTO: An overview and assessment of current practice. Journal of Process Control 2011, 21 (6), 874-884., 2011
  • Economides, M. J.; Nikolaou, M., Technologies for Oil and Gas Production: Present and Future. Aiche Journal 2011, 57 (8), 1974-1982., 2011
  • Guo, B. N.; Abdelraouf, K.; Ledesma, K. R.; Chang, K. T.; Nikolaou, M.; Tam, V. H., Quantitative Impact of Neutrophils on Bacterial Clearance in a Murine Pneumonia Model. Antimicrobial Agents and Chemotherapy 2011, 55 (10), 4601-4605., 2011
  • Tam, V. H.; Nikolaou, M., A Novel Approach to Pharmacodynamic Assessment of Antimicrobial Agents: New Insights to Dosing Regimen Design. Plos Computational Biology 2011, 7 (1)., 2011
  • Nikolaou, M., "Compressed Natural Gas" in Advanced Natural Gas Engineering, X. Wang and M. J. Economides, Gulf Publishing, 2009
  • Nikolaou, M., “Combating microbial resistance to antimicrobial agents through dosing regimen optimization,” Optimization in Medicine and Biology, G. Lim (Editor), Taylor & Francis, 2007. Link to file
  • Nikolaou, M., “Model Predictive Controllers: A Critical Synthesis of Theory and Industrial Needs,” Advances in Chemical Engineering Series, Academic Press, 2001. Link to file

  More publications in faculty website above.

• Patents

  • Tam, V. H., and M. Nikolaou, MODELING OF MICROBIAL (TUMOR) ADAPTATION TO ANTIMICROBIAL (CYTOTOXIC) AGENTS, D6678PCT; PCT/US2006/036458
    Date: 01/01/2013
  • Gerardo Mijares; Alejandro Garcia; Sathish Sankaran; Jose Rodriguez; Luigi Saputelli; Ankur Awasthi; and Michael Nikolaou, SYSTEMS AND METHODS FOR OPTIMIZATION OF REAL TIME PRODUCTION OPERATIONS, 20090157590
    Date: 05/01/2009
  • Economides, Michael J.; Deeg, Wolfgang F. J.; Valko, Peter; Nikolaou, Michael; andSankaran, Sathish, Method for stress and stability related measurements in boreholes, U.S. Patent 6,834,233, 2004

• Grants and Funded Research

  • $519,000 National Institutes of Health grant to research antibiotic-resistant bacteria, 2014
  • RPSEA multi-million dollar award to develop a self-teaching expert system for the analysis, design and prediction of gas production from tight gas reservoirs. 

• Curriculum Vitae

  • None available.

• Contact information

  Engineering Bldg 1, Room S228

  Phone: 713-743-4309 | Fax: 713-743-4323

  nikolaou@uh.edu