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Conducting Polymer Microcups for Organic Bioelectronics and Drug Delivery

Development of sensitive and selective biosensors and bioelectronics is of considerable interest for neural interface technologies. The performance of neural interfaces relies on the physical, chemical and electrical properties of the electrode materials, which enable long-lasting communications.

This templating method uses only poly (pyrrole) (PPy), a conducting polymer (CP) for fabrication of monodisperse conducting polymer microcups with tunable surface morphology, electrical properties, controlled drug loading and sustained drug release. Electrical conductivity and in-vitro drug-release profile for the PPy microcups have been characterized in the lab.

Applications

  • Bioelectronics
  • Drug delivery
  • Neural interface
  • Axonal regeneration

Problems Addressed

  • Existing electrodes utilize metallic materials and are not compatible with neural tissue
  • Incorporation of biomolecules using existing methods have shown to hinder electrical properties of CP's
  • Another challenge is creation of monodisperse CP microstructures with tunable surface morphology

Competitive Advantages

  • Capable of diagnosing impending complications in ESP's
  • Automatically generates solutions to correct and prevent the complication
  • Can extend the life expectancy of ESP's
  • Increases the production time of ESP's
  • Reduces production loss and replacement costs

Patents

  • PCT/US2018/047565

Publications