Magnetoresistive sensors (MR) are a possible alternative to fluorescent enzymatic biomarker assays for detecting presence or absence of a target molecule. Most MR sensors measure an analog resistance that is correlated to an amount of magnetic reporters. In contrast, this ultra –sensitive MR sensor is designed to digitally switch in the presence of a single or multiple reporters. The detection of the reporter in this binding assay corresponds to the presence of a target molecule. The inventors have already developed a prototype with complete software interface.
Research tool for biomarker detection
Fluorescent reporters require significant biomolecule to achieve high signal-noise ratio.
Suffer from issues related to sample turbidity, auto-fluorescence and photo bleaching.
This technology uses magnetic reporters that are stable enabling high sensitivity of detection.
Sensitivity to detect molecules at low femtomole concentrations
Sensitivity 100X better than commercial fluorescent based platforms