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Faculty Profile

Sanket PatelSanket Patel

Research Assistant Professor of Pharmacology
Department of Pharmacological and Pharmaceutical Sciences

Office: Health 2
University of Houston College of Pharmacy
4849 Calhoun, Room 5004A
Houston, TX 77204-5037

Contact: snpatel5@central.uh.edu - 713-743-3868

Research:

My research interest focuses on deciphering: 1. the tissue-protective mechanisms upon activation of angiotensin-II type 2 receptor, mainly in dysmetabolism, inflammation, and oxidative stress utilizing either genetic or diet-induced rodent models; 2. the physical and functional interactions among the angiotensin receptors and receptor Mas

  • St. John's University, New York, Ph.D. Pharmaceutical Sciences ('14) and M.S. Pharmaceutical Sciences ('09)
  • L.M. College of Pharmacy, Gujarat University, Ahmedabad, INDIA, Bachelor of Pharmacy, 2004
  • St. John's University Research Fellowship, 2013-14

ORCID Profile

Original Research Manuscripts

  • Fatima N, Patel SN, Hussain T (2021) Angiotensin AT2 receptor is anti-inflammatory and reno-protective in lipopolysaccharide mice model: Role of IL-10. Front Pharmacol, in print
  • Ali R, Patel SN, Hussain T (2021) Angiotensin type 2 receptor activation limits kidney injury during early phase and induces Treg cells during late phase of renal ischemia. Am J Physiol Renal Physiol, in print
  • Patel SN and Hussain T (2020) Synergism between angiotensin receptors ligands: role of angiotensin-(1-7) in modulating AT2R agonist response on nitric oxide in kidney cells. Pharmacol Res Perspect 8(6):e00667
  • Patel SN, Dhande IS, Gray EA, Ali Q, Hussain T (2019) Prevention of lipopolysaccharide-induced CD11b+ immune cell infiltration in the kidney: role of AT2 receptors. Biosci Rep 39(5):1-13
  • Nag S, Patel SN, Mani S, Hussain T (2019) Role of angiotensin type 2 receptor in improving lipid metabolism and preventing adiposity. Mol Cell Biochem 461(1-2):195-204
  • Patel SN, Ali Q, Steckelings UM, Hussain T (2017) Angiotensin II type 2 receptor and receptor Mas are functionally interdependent in obese Zucker rat kidney. Hypertension 70(4):831-838
  • Patel SN, Ali Q, Hussain T (2016) Angiotensin II type 2-receptor agonist C21 reduces proteinuria and oxidative stress in kidney of high-salt fed obese Zucker rats. Hypertension 67(5):906-915
  • Ali Q, Patel SN, Hussain T (2015) Angiotensin AT2 receptor agonist prevents salt-sensitive hypertension in obese Zucker rats. Am J Physiol Renal Physiol 308(12):F1379-F1385

Invited Reviews

  • Fatima N, Patel SN, Hussain T (2021) Angiotensin-II type 2 receptor: a protective target against hypertension, metabolic dysfunction, and organ remodeling. Hypertension, in print
  • Patel SN, Fatima N, Ali R, Hussain T (2020) Emerging role of angiotensin AT2 receptor in anti-inflammation: an update. Curr Pharm Des 26(4):492-500
  • Patel SN, Hussain T (2018) Dimerization of AT2 and Mas receptors in the control of blood pressure. Curr Hypertens Rep 20(5):41

Invited Editorial Commentaries

  • Patel SN, Tahir Hussain (2018) Role of angiotensin type 2 receptor in maintaining sodium-potassium balance. Hypertension 71(4):653-655
  • Patel SN, Narayan P, Goldberg ID, Naaz F, Hussain T, Ali Q (2018) Kidney appreciates stable blood pressure. Am J Hypertens 31(5):532-533

Awards & Honors

  • The Kidney Council New Investigator Award 2016 by American Heart Association
  • Biotex Laboratories Junior Scientist Award in Immunology 2019 by Association of Scientists of Indian Origin in America (ASIOA)