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Faculty Profile

Sanket PatelSanket Patel

Research Assistant Professor of Pharmacology
Department of Pharmacological and Pharmaceutical Sciences

University of Houston College of Pharmacy
Health 2, Room 5004A
4349 Martin Luther King Boulevard
Houston, TX 77204-5037

Contact: - 713-743-3868


My research interest focuses on deciphering: 1. the tissue-protective mechanisms upon activation of angiotensin-II type 2 receptor, mainly in dysmetabolism, inflammation, and oxidative stress utilizing either genetic or diet-induced rodent models; 2. the physical and functional interactions among the angiotensin receptors and receptor Mas

  • St. John's University, New York, Ph.D. Pharmaceutical Sciences ('14) and M.S. Pharmaceutical Sciences ('09)
  • L.M. College of Pharmacy, Gujarat University, Ahmedabad, INDIA, Bachelor of Pharmacy, 2004
  • St. John's University Research Fellowship, 2013-14

ORCID Profile

Original Research Manuscripts

  • Fatima N, Patel SN, Hussain T (2021) Angiotensin AT2 receptor is anti-inflammatory and reno-protective in lipopolysaccharide mice model: Role of IL-10. Front Pharmacol, in print
  • Ali R, Patel SN, Hussain T (2021) Angiotensin type 2 receptor activation limits kidney injury during early phase and induces Treg cells during late phase of renal ischemia. Am J Physiol Renal Physiol, in print
  • Patel SN and Hussain T (2020) Synergism between angiotensin receptors ligands: role of angiotensin-(1-7) in modulating AT2R agonist response on nitric oxide in kidney cells. Pharmacol Res Perspect 8(6):e00667
  • Patel SN, Dhande IS, Gray EA, Ali Q, Hussain T (2019) Prevention of lipopolysaccharide-induced CD11b+ immune cell infiltration in the kidney: role of AT2 receptors. Biosci Rep 39(5):1-13
  • Nag S, Patel SN, Mani S, Hussain T (2019) Role of angiotensin type 2 receptor in improving lipid metabolism and preventing adiposity. Mol Cell Biochem 461(1-2):195-204
  • Patel SN, Ali Q, Steckelings UM, Hussain T (2017) Angiotensin II type 2 receptor and receptor Mas are functionally interdependent in obese Zucker rat kidney. Hypertension 70(4):831-838
  • Patel SN, Ali Q, Hussain T (2016) Angiotensin II type 2-receptor agonist C21 reduces proteinuria and oxidative stress in kidney of high-salt fed obese Zucker rats. Hypertension 67(5):906-915
  • Ali Q, Patel SN, Hussain T (2015) Angiotensin AT2 receptor agonist prevents salt-sensitive hypertension in obese Zucker rats. Am J Physiol Renal Physiol 308(12):F1379-F1385

Invited Reviews

  • Fatima N, Patel SN, Hussain T (2021) Angiotensin-II type 2 receptor: a protective target against hypertension, metabolic dysfunction, and organ remodeling. Hypertension, in print
  • Patel SN, Fatima N, Ali R, Hussain T (2020) Emerging role of angiotensin AT2 receptor in anti-inflammation: an update. Curr Pharm Des 26(4):492-500
  • Patel SN, Hussain T (2018) Dimerization of AT2 and Mas receptors in the control of blood pressure. Curr Hypertens Rep 20(5):41

Invited Editorial Commentaries

  • Patel SN, Tahir Hussain (2018) Role of angiotensin type 2 receptor in maintaining sodium-potassium balance. Hypertension 71(4):653-655
  • Patel SN, Narayan P, Goldberg ID, Naaz F, Hussain T, Ali Q (2018) Kidney appreciates stable blood pressure. Am J Hypertens 31(5):532-533

Awards & Honors

  • The Kidney Council New Investigator Award 2016 by American Heart Association
  • Biotex Laboratories Junior Scientist Award in Immunology 2019 by Association of Scientists of Indian Origin in America (ASIOA)