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Faculty Profile

wu-lei.jpgLei Wu

Research Assistant Professor of Pharmaceutics
Department of Pharmacological and Pharmaceutical Sciences

Office: 
University of Houston College of Pharmacy
Health 2, Room 7052
4349 Martin Luther King Boulevard
Houston, TX 77204-5039

Contact: lwu7@uh.edu - 281-615-1539 - Fax: 713-795-8305

Research:

Biopharmaceutical analysis, preclinical pharmacokinetics study in animal models, and pharmacokinetics/pharmacodynamics (PK/PD) modeling in preclinical and clinical studies.

  • Ph.D. Pharmaceutics, University of Houston College of Pharmacy, Houston, TX
  • Bachelor of Pharmacy, China Pharmaceutical University, Nanjing, China
  • Licensed Pharmacist (China)
  • Certified Assistant Engineer (China)

Google Scholar Profile
  • Ashley Nguyen, Diana S-L. Chow, Lei Wu, Yang Teng, Mahua Sarkar, Elizabeth G Toups, James S Harrop, Karl M Schmitt, Michele M Johnson, James D Guest, Bizhan Aarabi, Christopher I Shaffrey, Maxwell Boakye, Ralph F Frankowski, Michael G Fehlings, Robert G Grossman, Longitudinal impacts of acute spinal cord injury on clinical pharmacokinetics of riluzole, a potential neuroprotective agent, The Journal of Clinical Pharmacology. https://doi.org/10.1002/jcph.1876. 2021 Apr.
  • X Gao, L Wu, RYL Tsai, J Ma, X Liu, DSL Chow, D Liang, H Xie, Pharmacokinetic Model Analysis of Supralingual, Oral and Intravenous Deliveries of Mycophenolic Acid, Pharmaceutics, 13 (4), 574, 2021 Apr.
  • Chityala, L Wu, DSL Chow, R Ghose, Effects of inflammation on irinotecan pharmacokinetics and development of a best-fit PK model, Chemico-biological interactions, 316, 108933, 2020 Jan.
  • Ashley Nguyen, Lei Wu, Angela Teng, Mahua Sarkar, Elizabeth Toups, Robert Grossman, Diana Chow, Effects of concomitant medications on pharmacokinetics of riluzole therapy in patients with acute spinal cord injury, Journal of Neurotrauma. 36(13): A52. 2019 Jul.
  • Daping Zhang, Lei Wu, Diana S.-L. Chow, Vincent H. Tam, Danielle R. Rios, Quantitative determination of dopamine in human plasma by a highly sensitive LC-MS/MS assay: Application in preterm neonates, Journal of Pharmaceutical and Biomedical Analysis, 117: 227-231, 2016.
  • Wu L, Boyd JL, Daniels V, Wang Z, Chow DS, Putcha L. Dose escalation pharmacokinetics of intranasal scopolamine gel formulation. J Clin Pharmacol. 55(2): 195-203, 2015.
  • Weeks PA, Teng Y, Wu L, Sun M, Yang Z, Chow DS. Chemical and physical compatibility of an intravenous solution of epinephrine with calcium chloride. Int J Pharm Compd. 2014 MarApr;18(2):152-8.
  • Cui Z, Chow DS, Wu L, Lazar DA, Rodrigo R, Olutoye OO, Olutoye OA. High performance liquid chromatography-tandem mass spectrometric assay of dexmedetomidine in plasma, urine and amniotic fluid samples for pregnant ewe model. J Chromatogr B Analyt Technol Biomed Life Sci. 2014 961: 13- 19.
  • John J, John M, Wu L, Hsiao C, Abobo CV, Liang D.Effects of etravirine on the pharmacokinetics and pharmacodynamics of warfarin in rats. Br J Pharmacol. 2013 Apr; 168(8):1851-8. doi: 10.1111/bph.12082.
  • Yin J, Lu K, Lin J, Wu L, Hildebrandt MA, Chang DW, Meyer L, Wu X, Liang D. Genetic variants in TGF-β pathway are associated with ovarian cancer risk. PLoS One. 2011; 6(9):e25559.
  • Cyril Abobo, Lei Wu, Mathew Kizhakkekara, Jyothy John, Dong Liang. LC-MS/MS determination of etravirine in rat plasma and its application in pharmacokinetic studies. J Chromatogr B Analyt Technol Biomed Life Sci. 2010 Nov 15; 878(30):3181-6.

Awards & Honors

  • PPS Research Symposium, 2nd Prize for podium presentation, 2018
  • First Award Fellowship from the National Space Biomedical Research Institute (NSBRI), 2015
  • Student/Trainee Awards, American College of Clinical Pharmacology, 2012, 2014, and 2015