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Faculty Profile

Krishna BoiniAnees Banday

Research Professor of Pharmacology
Department of Pharmacological and Pharmaceutical Sciences

Office: 
University of Houston College of Pharmacy
Health 2, Room 6008
4349 Martin Luther King Boulevard
Houston, TX 77204-5037

Contact: abanday@uh.edu - Office: 713-743-1418 - Fax: 713-743-1884

Research:

Mechanisms and role of oxidative stress in renal dopamine receptor dysfunction and hypertension

  • Ph.D. Biochemistry, Aligarh Muslim University
  • M.Sc. Biochemistry, Aligarh Muslim University
  • B.Sc. (Honours) Biochemistry, Aligarh Muslim University

  • Farooqui Z, Mohammad RS, Lokhandwala MF, Banday AA. Nrf2 inhibition induces oxidative stress, renal inflammation and hypertension in mice. Clin Exp Hypertens. 2021 Feb 17;43(2):175-180. doi: 10.1080/10641963.2020.1836191. Epub 2020 Oct 18.
  • Pokkunuri ID, Lokhandwala MF, Banday AA. Protein disulfide isomerase inhibition impairs Keap1/Nrf2 signaling and mitochondrial function and induces apoptosis in renal proximal tubular cells. Am J Physiol Renal Physiol. 2020 Oct 1;319(4):F686-F696. doi: 10.1152/ajprenal.00049.2020. Epub 2020 Aug 24.
  • Banday AA, Lokhandwala MF. Renal Dopamine Oxidation and Inflammation in High Salt Fed Rats. J Am Heart Assoc. 2020 Jan 7;9(1):e014977. doi: 10.1161/JAHA.119.014977. Epub 2019 Dec 27.
  • Banday AA, Diaz AD, Lokhandwala M. Kidney dopamine D1-like receptors and angiotensin 1-7 interaction inhibits renal Na+ transporters. Am J Physiol Renal Physiol. 2019 Oct 1;317(4):F949-F956. doi: 10.1152/ajprenal.00135.2019. Epub 2019 Aug 14.
  • Banday AA, Lokhandwala MF. Oxidative stress impairs cGMP-dependent protein kinase activation and vasodilator-stimulated phosphoprotein serine-phosphorylation. Clin Exp Hypertens. 2019;41(1):5-13. doi: 10.1080/10641963.2018.1433197. Epub 2018 Feb 9.
  • Banday AA. Chronic insulin treatment phosphorylates the renal Na-K-ATPase α1-subunit at serine 16/23 and reduces its activity involving PI3-kinase-dependent PKC activation. Am J Physiol Renal Physiol. 2016 Nov 1;311(5):F958-F966. doi: 10.1152/ajprenal.00355.2016. PMID: 27605582
  • Bhatt SR, Lokhandwala MF, Banday AA. Vascular oxidative stress upregulates angiotensin II type I receptors via mechanisms involving nuclear factor kappa B. Clin Exp Hypertens. 2014;36(6):367-73. doi: 10.3109/10641963.2014.943402. PMID: 25198883
  • Banday AA, Lokhandwala MF. Novel gastro-renal axis and sodium regulation during hypertension. Hypertension. 2013 Nov;62(5):834-5. doi: 10.1161/HYPERTENSIONAHA.113.01799. PMID: 24019398
  • Banday AA, Lokhandwala MF. Transcription factor Nrf2 protects renal dopamine D1 receptor function during oxidative stress. Hypertension. 2013 Sep;62(3):512-7. doi: 10.1161/HYPERTENSIONAHA.113.01358. PMID: 23876469
  • Javkhedkar AA, Lokhandwala MF, Banday AA. Defective Nitric Oxide Production Impairs Angiotensin II-Induced Na/K-ATPase Regulation in Spontaneously Hypertensive Rats. Am J Physiol Renal Physiol. 2012 Jan;302(1):F47-51. PMID: 21900450
  • Bhatt SR, Lokhandwala MF, Banday AA. Resveratrol prevents endothelial nitric oxide synthase uncoupling and attenuates development of hypertension in spontaneously hypertensive rats. Eur J Pharmacol. 2011 Sep 30;667(1-3):258-64.
  • Banday AA, Lokhandwala MF. Angiotensin II-mediated biphasic regulation of proximal tubular Na+/H+ exchanger 3 is impaired during oxidative stress. Am J Physiol Renal Physiol. 2011 Aug;301(2):F364-70.
  • Banday, A.A. and Lokhandwala, M.F.: Oxidative stress causes renal angiotensin II type 1 receptor upregulation, Na+/H+ exchanger 3 overstimulation and hypertension. Hypertension, 57: 452-459, 2011.
  • Muhammad, A.B., Lokhandwala, M.F. and Banday, A.A.: Exercise reduces oxidative stress but does not alleviate hyperinsulinemia or renal dopamine D1 receptor dysfunction in obese Zucker rats. Amer J Physiol: Renal Physiol, 300:F98-F104, 2011.
  • Banday AA, Lokhandwala MF. Inhibition of natriuretic factors increases blood pressure in rats. Am J Physiol Renal Physiol. 2009 Aug;297(2):F397-402.

Awards & Honors

  • Young Investigator Award, American Society of Nephology

Involvement

  • Council for High Blood Pressure Research, American Heart Association
  • American Society of Nephrology
  • Qualified CSIR-UGC-NET-97 conducted jointly by Council of Scientific and Industrial Research (C.S.I.R) and University Grants Commission (U.G.C.), Government of India