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Bioresponsive Iron Oxide Nanoparticles as Magnetic Resonance (MR) Probes And Ultrasmall superparamagnetic iron oxide nanoparticles and uses thereof

The Innovation

Design, synthesis, and use of novel biomimetic ultrasmall paramagnetic iron oxide nanoparticles with dual bioresponsive elements capable of selectively targeting tumor cells.

Competitive Edge

Selectivity to tumor cells. Dual bioresponsive elements. Stealth MR probes that are targeted. Dual functioning – imaging & pathophysiological information. Contrast agents in the market – Feridex, Ferumoxil, Ferumoxitran, magnetophages, (SPIO)-anti-c-MET, RGDS-USPIO

Future uses: Ultimodal system for drug and gene delivery in addition to imaging

Targeted Market

Oncological imaging, pharmaceutical industry for combination imaging and therapy.