College of Pharmacy Faculty
Department of Pharmacological and Pharmaceutical Sciences

Ming Hu, Ph.D.
Professor of Pharmaceutics
UH College of Pharmacy
Texas Medical Center Campus, Room 531
1441 Moursund Street
Houston, TX 77030
713-795-8320
713-795-8305 (Fax)

mhu@uh.edu


Education
B.S. in Pharmacy, Shanghai First Medical College
Ph.D. in Pharmaceutics, University of Michigan, Ann Arbor, Michigan
Post-doc in Pharmaceutical Chemistry, University of Kansas, Lawrence, Kansas
Sabbatical, National Cancer Institute, Laboratory of Metabolism, Bethesda, Maryland

Courses:
PCEU 6341: Advanced Pharmacokinetics
PCEU 6345: Advanced Pharmaceutics II

Research Interests:
Dr. Hu is an expert in the intestinal absorption and metabolisms of drugs, natural chemicals and dietary ingredients. Dr. Hu has conceptualized the “Enteric Recycling” as a process of xenobiotic disposition, and proposed the “Revolving Door” theory to understand the coupling between conjugating enzyme and efflux transporters. In addition to oral absorption and metabolism, he has also pioneered the concept of lipozyme, a nanoreactor for detoxification. Dr. Hu’s laboratory uses two state of the art oral absorption techniques: Caco-2 cell culture model and perfused rat intestinal model. Currently, his laboratory is interested in developing pills for prevention of colon and hormone related cancers (e.g., breast and prostate). One of his ongoing research projects is to improve the bioavailability of chemopreventive agents. Others are focusing on purifying anticancer ingredients of herbal materials and decreasing the bioavailability of dietary carcinogens. Dr. Hu has published more than 40 peer reviewed journal articles and 7 review articles and book chapters.

Honors:
Visiting Professor, University of Valencia, Valencia, Spain, 2000
Visiting Professor, National University of Singapore, Singapore, 2001
Visiting Professor, Shanghai Institute of Pharmaceutical Industries, Shanghai, China, 2003-2006
Editorial Board Member, Journal of Alternative and Complementary Medicine
Editorial Board Member, Molecular Pharmaceutics
Reviewer, U.S. Civilian Research and Development Foundation (2001)
Reviewer, National Science Foundation SBIR Program (2002)
Reviewer, National Cancer Institute: Special Emphasis Panel (RFA-CA-03-003) (Nov, 2002)
Reviewer, National Institutes of Health, Metabolic Pathology Study Section (ad hoc member 2003)
Reviewer, National Institutes of Health, Chemo/Dietary Prevention Study Section (2003-present)
Reviewer, National Cancer Institute, NCI FLAIR program (PA-01-01) (2003)
Reviewer, National Cancer Institute, Small Grant Program in Cancer Prevention (2003)
Reviewer, National Institute of Ageing. P01 Grant Review, University of Illinois at Champaign-Urbana (2004)

Professional Affiliation:
American Society of Pharmacology and Experimental Therapeutics (elected 1996)
American Association of Pharmaceutical Scientists (joined in 1986)

Selected Publications