Tam VH,
Chang KT, LaRocco MT, Schilling AN, McCauley SK, Poole K, Garey
KW. Prevalence and mechanisms of carbapenem resistance in bloodstream
isolates of Pseudomonas aeruginosa. Diagn Microbiol Infect Dis
2007; 58(3): 309-14
Tam VH, Louie A, Fritsche TR, Deziel M, Liu W,
Brown DL, Deshpande L, Leary R, Jones RN, Drusano GL. Impact of
drug exposure intensity and duration of therapy on emergence of
Staphylococcus aureus resistnace to a quinolone antimicrobial.
J Infect Dis 2007; 195(12): 1818-27
Kwa AL, Low JGH, Lee E, Kurup A, Chee HL, Tam VH.
The impact of multi-drug resistance on the outcomes of critically
ill patients with gram-negative bacterial pneumonia. Diagn Microbiol
Infect Dis 2007; 58: 99-104
Tam VH, Schilling AN, LaRocco MT, Gentry LO,
Lolans K, Quinn JP, Garey KW. Prevalence of AmpC over-expression
in bloodstream isolates of Pseudomonas aeruginosa. Clin Microbiol
Infect 2007; 13(4): 413-8
Tam VH, Louie A, Deziel MR, Liu W, Drusano GL.
The relationship between quinolone exposures and resistance amplification
is characterized by an inverted-U: a new paradigm for optimizing
pharmacodynamics to counter-select resistance. Antimicrob Agents
Chemother 2007; 51(2): 744-7
Falagas ME, Bliziotis IA, Tam VH. Intraventricular
or intrathecal use of polymyxins for patients with Gram-negative
meningitis: a systematic review of the available evidence. Int
J Antimicrob Agents 2007; 29(1): 9-25
Tam VH, Kabbara S,
Yeh RF, Leary RH. Impact of sample size on the performance of
multiple-model pharmacokinetic simulations. Antimicrob Agents
Chemother 2006; 50(11): 3950-2
Wang S, Chen J, Jia X, Tam VH, Hu M. Disposition
of flavonoids via enteric recycling: comparison of intestinal
disposition of six isoflavones with respect to structural differences.
Drug Metab Dispos 2006; 34(11): 1837-48
Tam VH, Kabbara S. Comparative performance of
different methods to simulate drug exposure and variability in
a population. Diagn Microbiol Infect Dis 2006; 56(2): 185-8
Garey KW, Kumar N, Dao T, Tam VH, Gentry LO.
Risk factors for postoperative surgical site infections due to
gram-negative bacteria in cardiac surgery patients. J Chemother
2006; 18(4): 402-8
Boucher AN, Tam VH. Mathematical formulation
of additivity for antimicrobial agents. Diagn Microbiol Infect
Dis 2006; 55: 319-325
Tam VH, Kabbara S, Vo G, Schilling AN, Coyle
EA. Comparative pharmacodynamics of gentamicin against Staphylococcus
aureus and Pseudomonas aeruginosa. Antimicrob Agents Chemother
2006; 50(8): 2626-31
Tam VH, Adams S, LaRocco
MT, Gerard LN, Gentry LO, Garey KW. An integrated pharmacoeconomic
approach for antimicrobial formulary decision making. Am J Health
Syst Pharm 2006; 63(8): 735-9
Lodise TP, Rhoney DH, Tam VH, Parker D, McKinnon
PS, Drusano GL. Pharmacodynamic profiling of cefepime in plasma
and cerebrospinal fluid of hospitalized patients with external
ventriculostomies. Diagn Microbiol Infect Dis 2006; 54(3): 223-30
Nikolaou M, Tam VH. A new modeling approach to
the effect of antimicrobial agents on heterogeneous microbial
populations. J Math Biol 2006; 52(2): 154-82
Wiederhold NP, Tam VH, Chi J, Prince RA, Kontoyiannis
DP, Lewis RE. Pharmacodynamic activity of amphotericin B deoxycholate
is associated with peak plasma concentrations in a neutropenic
murine model of invasive pulmonary aspergillosis. Antimicrob Agents
Chemother 2006; 50(2): 469-473
Jumbe NL, Louie A, Miller MH, Liu W, Deziel MR, Tam VH,
Bachhawat R, Drusano GL. Quinolone efflux pumps play a central
role in emergence of fluoroquinolone resistance in Streptococcus
pneumoniae. Antimicrob Agents Chemother 2006; 50(1): 310-7
Tam VH, Schilling AN, Neshat S, Poole K, Melnick
DA, Coyle EA. Optimization of meropenem minimum concentration/MIC
ratio to suppress in vitro resistance of Pseudomonas aeruginosa.
Antimicrob Agents Chemother 2005; 49(12): 4920-7
Tam VH, Nikolaou M. Mathematical modeling of
resistance emergence. J Antimicrob Chemother 2005; 56(5): 983
Chen J, Wang S, Jia X, Bajimaya S, Lin H, Tam VH,
Hu M. Disposition of flavonoids via recycling: comparison of intestinal
versus hepatic disposition. Drug Metab Dispos 2005; 33(12): 1777-84
Nikolaou M, Misra P, Tam VH, Bailey III AD. Complexity
in semiconductor manufacturing, activity of antimicrobial agents,
and drilling of hydrocarbon wells: common themes and case studies.
Computers and Chem Eng 2005; 29: 2266-89
Tam VH, Schilling AN, Vo G, Kabbara S, Kwa AL,
Wiederhold NP, Lewis RE. Pharmacodynamics of polymyxin B against
Pseudomonas aeruginosa. Antimicrob Agents Chemother 2005; 49(9):
3624-30
Kwa ALH, Loh C, Low JGH, Kurup A, Tam VH. Nebulized
colistin in the treatment of pneumonia due to multidrug resistant
Acinetobacter baumannii and Pseudomonas aeruginosa. Clin Infect
Dis 2005; 41(5): 754-7
Walker PW, Neuhauser MM, Tam VH, Willey JS, Palmer
JL, Bruera E, Prince RA. Subcutaneous administration of cefepime.
J Pain Symptom Manage 2005; 30(2): 170-4
Tam VH, Louie A, Deziel MR,
Liu W, Leary R, Drusano GL. Bacterial population responses to
drug selective pressure: examination of garenoxacin against Pseudomonas
aeruginosa. J Infect Dis 2005; 191(3): 420-8
