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Profile: Samina Salim

Samina Salim
Samina Salim, Ph.D.
Associate Professor of Pharmacology
Department of Pharmacological & Pharmaceutical Sciences
Physical Address: Science and Research Building 2, 3455 Cullen Blvd., Room 557, Houston, TX 77204-5037
Mailing Address: Health and Biomedical Sciences Building 2, 4849 Calhoun Road, Room 3044, Houston, TX 77204-5037

Office: 713-743-1776
Fax: 713-743-1229
ssalim@uh.edu

Education

B.S, Biochemistry, Aligarh Muslim University, Aligarh, India

M.S., Biochemistry, Aligarh Muslim University, Aligarh, India

Ph.D., Biochemistry, Aligarh Muslim University, Aligarh, India

Post-doctoral Fellow, Department of Integrative Biology and Pharmacology, University of Texas Health Science Center at Houston, TX; and Department of Medical Biochemistry Biophysics, Karolinska Institutet, Stockholm, Sweden

Research Interests

We are interested in studying how biochemical changes in the brain contribute to anxiety disorders. Our primary focus is to investigate a potentially causal role of oxidative stress in these disorders. Behavioral, pharmacological, biochemical and immunohistochemical approaches in neuronal cell culture and rodent models of oxidative stress are utilized to examine mechanistic underpinnings of anxiety disorders. Involvement of oxidative stress in comorbid prevalence of anxiety disorders with cognitive impairment and hypertension, also are being explored.

Current research projects in my laboratory include a National Institute of Mental Health (NIMH) funded project, which is focused on determining role of antioxidant defense mechanism mediated by a Regulator of G-Protein Signaling Protein (RGS)-2 in anxiety-like behavior of rats. Involvement of PKC, p38 MAPK and calpains in regulation of these mediators specifically involvement of antioxidant defense enzymes including glutathione reductase 1 and glyoxalase 1 in anxiety-like behavior of rats is being examined. Our recent work has identified that induction of oxidative stress via pharmacological intervention or via induction of psychological stress of acute sleep-deprivation, both lead to anxiety-like behavior in rats. We also have observed a causal role of oxidative stress in hypertension, and learning and memory impairment in rats. Projects are underway to investigate a deeper understanding of the underlying biology of some of these debilitating disorders.

Research Support

Ongoing

Agency: National Institute of Mental Health (NIMH); NIHR15
Project Title: “Oxidative Stress-A Potential Recipe for Anxiety-like behavior”
Role: Principal Investigator

Completed

Agency: Grant to Advance and Enhance Research (GEAR), University of Houston
Project Title: “Neuronal RGS2 Expression: Mechanisms and Implications In Oxidative Stress and Anxiety”
Role: Principal Investigator

Agency: NIH, R15MH093918-01A1
Project Title: “Oxidative Stress-A Potential Recipe for Anxiety-like behavior”
Status: 2012-2015
Role: Principal Investigator

Agency: American Heart Association, Texas Affiliate Grant No.: 0555032Y
Project Title: Regulation of Alpha2-Adrenceptor Down-Regulation by GRK3
Award Date: July 1, 2005 to June 30, 2007
Role: Collaborating Investigator (PI: Eikenburg)

Agency: NARSAD (National Alliance For Research on Schizophrenia and Depression)
Grant No: 93041
Project Title: Regulation of GRK3 Expression, A Critical Modulator of Signaling in Bipolar Disorder
Award Date: Sept. 2006-2008
Role: Co-Investigator (PI: Eikenburg)

Awards & Honors

Honors & Awards

  • Symposium session chair, Session title: “Stress and Behavior,” Budapest, Hungry, June 7-9, International Society of Behavioral Neuroscience (IBNS), 2016
  • Council Member, Association of Scientists of Indian Origin in America (ASIOA), 2016
  • Session chair, Association of Scientists of Indian Origin (ASIO) annual meeting, Orlando, Florida, January 19-20, 2015
  • Excellence in Research Award, College of Pharmacy, University of Houston, TX, 2015
  • Early Faculty Award for Mentoring Undergraduate Research, University of Houston, TX, 2015
  • Invited Attendee, ACNP, Hollywood, Florida, 2015
  • Invited Attendee, ACNP, Hollywood, Florida, 2014
  • Invited attendee, American College of Neuropsychopharmacology (ACNP) annual meeting, Miami, Florida, 2010
  • Judge, Behavioral Neuropharmacology Poster Session, Experimental Biology, New Orleans, LA, 2010
  • Sarraj, N., Taneja M., Chugh C. Hovatta I and Salim, S. Treadmill Exercise Prevents Oxidative Stress-Induced Anxiety-Like Behavior in Rats. Selected for “Posters on the Hill,” National Council for Undergraduate Research (CUR), Capitol Hill, Washington D.C. April 13, 2010. Mentor and Mentee Travel Award
  • Judge, Behavioral Neuropharmacology Poster Session, Experimental Biology, San Diego, CA., 2008
  • Travel award, RGS Protein Colloquium, Experimental Biology, San Diego, CA, 2007
  • Judge, National Student Research Forum, University of Texas Medical Branch, Galveston, TX, 2004

Research Recognition

  • Featured in “Pharmacologist,” a newsletter of the ASPET, December issue, 2015
  • Publication entitled, “Grape Powder Supplementation Prevents Oxidative Stress-Induced Anxiety-Like Behavior, Memory Impairment and High Blood Pressure in Rats” selected by The American Society for Nutrition (ASN) for video JN video pubcast, 2013
  • UH media release on Posters on the Hill honor, April 2010
  • Research featured in University of Houston newspaper, The Daily Cougar, 04/02/2010
  • Research featured in Katy Newspaper, 04/15/2010
  • Special citation on SFN publication, “Why exercise makes you less anxious?”, New York Times, November, 18, 2009
  • Special citation of the publication “Salim, S. and Eikenburg, DC. J. Phamacol. Exptl. Ther. 320:1106-1112,” featured in the Nascent Transcripts Emerging concepts from the recent literature), Molecular Interventions, Vol 7(1), 2007

Courses

  • PCOL 7350 Cellular Pharmacology
  • PCOL 6370 Advanced Pharmacology II
  • PHAR 4301 Cellular Life Sciences II
  • PHAR4421 Organ System Life Sciences II
  • PHAR 4400 Cellular Life Sciences I

Selected Publications

Behavioral effects of early life maternal trauma witness in rats. Liu H, Patki G, Salvi A, Kelly M, Salim S. Prog Neuropsychopharmacol Biol Psychiatry. 2017 Oct 23. pii: S0278-5846(17)30642-5. doi: 10.1016/j.pnpbp.2017.10.013. [Epub ahead of print] PMID:29074097

Psychological Impact of Vehicle Exhaust Exposure: Insights from an Animal Model. Salvi A, Patki G, Liu H, Salim S. Sci Rep. 2017 Aug 16;7(1):8306. doi: 10.1038/s41598-017-08859-1. PMID:28814807

Salim S. Oxidative Stress and the Central Nervous System. J Pharmacol Exp Ther. 2017 Jan;360(1):201-205. PubMed PMID: 27754930; PubMed Central PMCID: PMC5193071. Invited review (peer reviewed)

Salvi A, Patki G, Khan E, Asghar M and Salim S*. Protective Effect of Tempol in Buthionine sulfoximine (BSO)-induced oxidative stress in hippocampal derived HT22 cells. Oxid Med Cell Longev. 2016;2016:5059043. doi: 10.1155/2016/5059043. Epub 2016 Mar 16. *corresponding author

Samina Salim. Oxidative stress: a potential link between emotional wellbeing and immune response. Invited peer-reviewed review article. Current Opinion in Pharmacology. Curr Opin Pharmacol. 2016 Jul 8;29:70-76. doi: 10.1016/j.coph.2016.06.006. [Epub ahead of print] Review. PubMed PMID: 27400336. Invited review (peer reviewed)

Solanki N, Atrooz F, Asghar S, Salim S*. Tempol protects sleep-deprivation induced behavioral deficits in aggressive male Long-Evans rats. Neurosci Lett. 2015 Dec 23;612:245-250. doi: 10.1016/j.neulet.2015.12.032. [Epub ahead of print] PubMed PMID: 26724222. *corresponding author

Patki G, Salvi A, Liu H, Salim S*. Witnessing traumatic events and post-traumatic stress disorder: Insights from an animal model. Neurosci Lett. 2015 Jul 23;600:28-32. doi: 10.1016/j.neulet.2015.05.060. Epub 2015 Jun 1. PubMed PMID: 26044989. *corresponding author

Patki G, Ali Q, Pokkunuri I, Asghar M, Salim S*. Grape powder treatment prevents anxiety-like behavior in a rat model of aging. Nutr Res. 2015 Jun;35(6):504-11. doi: 10.1016/j.nutres.2015.05.005. Epub 2015 May 15. PubMed PMID: 26022140. *corresponding author

Solanki N, Alkadhi I, Atrooz F, Patki G, Salim S*. Grape powder prevents cognitive, behavioral, and biochemical impairments in a rat model of posttraumatic stress disorder. Nutr Res. 2015 Jan;35(1):65-75. doi: 10.1016/j.nutres.2014.11.008. Epub 2014 Dec 5. PubMed PMID: 25533441; PubMed Central PMCID: PMC4329242. *corresponding author

Patki G, Salvi A, Liu H, Atrooz F, Alkadhi I, Kelly M, Salim S*. Tempol treatment reduces anxiety-like behaviors induced by multiple anxiogenic drugs in rats. PLoS One. 2015 Mar 20;10(3):e0117498. doi: 10.1371/journal.pone.0117498. eCollection 2015. PubMed PMID: 25793256; PubMed Central PMCID: PMC4367986. *corresponding author

Patki G, Atrooz F, Alkadhi I, Solanki N, Salim S*. High aggression in rats is associated with elevated stress, anxiety-like behavior, and altered catecholamine content in the brain. Neurosci Lett. 2015 Jan 1;584:308-13. doi: 10.1016/j.neulet.2014.10.051. Epub 2014 Nov 1. PubMed PMID: 25450144; PubMed Central PMCID: PMC4322760. *corresponding author

Patki G, Solanki N, Salim S*. Witnessing traumatic events causes severe behavioral impairments in rats. Int J Neuropsychopharmacol. 2014 Dec;17(12):2017-29. doi: 10.1017/S1461145714000923. Epub 2014 Jun 2. PubMed PMID: 24887568; PubMed Central PMCID: PMC4318493. *corresponding author

Patki G, Solanki N, Atrooz F, Ansari A, Allam F, Jannise B, Maturi J, Salim S*. Novel mechanistic insights into treadmill exercise based rescue of social defeat-induced anxiety-like behavior and memory impairment in rats. Physiol Behav. 2014 Apr 13;130C:135-144. doi: 10.1016/j.physbeh.2014.04.011. [Epub ahead of print] PubMed PMID: 24732411. *corresponding author

Patki G, Li L, Allam F, Solanki N, Dao AT, Alkadhi K, Salim S*. Moderate treadmill exercise rescues anxiety and depression-like behavior as well as memory impairment in a rat model of posttraumatic stress disorder. Physiol Behav. 2014 Mar 19;130C:47-53.[Epub ahead of print] PubMed PMID: 24657739. *corresponding author

Salim S. Oxidative stress and psychological disorders. Curr Neuropharmacol. 2014 Mar;12(2):140-7. doi: 10.2174/1570159X11666131120230309. PubMed PMID: 24669208; PubMed Central PMCID: PMC3964745.

Neurobiological Consequences of Oxidative Stress. Special Edition in Current Neuropharmacology, Editors Salim S and Alkadhi KA. Curr Neuropharmacol. 2014 March. Mar; 12(2): 99. Published online 2014 Mar. doi: 10.2174/1570159X1202140307122223 PMCID: PMC3964751

Alkadhi KA and Salim S*. Neurobiological Consequences of Oxidative Stress. Special Edition in Current Neuropharmacology, Volume 12, Number 2, 2014. Pp 99-99, DOI: 10.2174/1570159X1202140307122223. *corresponding author

Dao AT, Zagaar MA, Salim S, Eriksen JL, Alkadhi KA. Regular exercise prevents non-cognitive disturbances in a rat model of Alzheimer's disease. Int J Neuropsychopharmacol. 2014 Apr;17(4):593-602. doi: 10.1017/S1461145713001351. Epub 2013 Nov 14. PubMed PMID: 24229510. 

Alkadhi K, Zagaar M, Alhaider I, Salim S, Aleisa A. Neurobiological consequences of sleep deprivation. Curr Neuropharmacol. 2013 May;11(3):231-49. doi: 10.2174/1570159X11311030001. PubMed PMID: 24179461; PubMed Central PMCID: PMC3648777.

Patki G, Solanki N, Atrooz F, Allam F, Salim S*. Depression, anxiety-like behavior and memory impairment are associated with increased oxidative stress and inflammation in a rat model of social stress. Brain Res. 2013 Nov 20;1539:73-86. doi: 10.1016/j.brainres.2013.09.033. Epub 2013 Oct 3. PubMed PMID: 24096214. *corresponding author

Patki G, Allam FH, Atrooz F, Dao AT, Solanki N, Chugh G, Asghar M, Jafri F, Bohat R, Alkadhi KA, Salim S*. Grape powder intake prevents ovariectomy-induced anxiety-like behavior, memory impairment and high blood pressure in female Wistar rats. PLoS One. 2013 Sep 9;8(9):e74522. PubMed PMID: 24040270; PubMed Central PMCID: PMC3767647. *corresponding author

Chugh G, Asghar M, Patki G, Bohat R, Jafri F, Allam F, Dao AT, Mowrey C, Alkadhi K, Salim S*. A high-salt diet further impairs age-associated declines in cognitive, behavioral, and cardiovascular functions in male Fischer brown Norway rats. J Nutr. 2013 Sep;143(9):1406-13. doi: 10.3945/jn.113.177980. Epub 2013 Jul 17. PubMed PMID: 23864508; PubMed Central PMCID: PMC3743272. *corresponding author

Dao AT, Zagaar MA, Levine AT, Salim S, Eriksen JL, Alkadhi KA. Treadmill exercise prevents learning and memory impairment in Alzheimer's disease-like pathology. Curr Alzheimer Res. 2013 Jun;10(5):507-15. PubMed PMID: 23627709; PubMed Central PMCID: PMC4004077.

Allam F, Dao AT, Chugh G, Bohat R, Jafri F, Patki G, Mowrey C, Asghar M, Alkadhi KA, Salim S*. Grape powder supplementation prevents oxidative stress-induced anxiety-like behavior, memory impairment, and high blood pressure in rats. J Nutr. 2013 Jun;143(6):835-42. doi: 10.3945/jn.113.174649. Epub 2013 Apr 17. PubMed PMID: 23596160; PubMed Central PMCID: PMC3652881. *corresponding author

Salim S*, Chugh G, Asghar M. Inflammation in anxiety. Adv Protein Chem Struct Biol. 2012;88:1-25. doi: 10.1016/B978-0-12-398314-5.00001-5. Review. PubMed PMID:22814704. *corresponding author

Zoladz PR, Park CR, Halonen JD, Salim S, Alzoubi KH, Srivareerat M, Fleshner M, Alkadhi KA, Diamond DM. Differential expression of molecular markers of synaptic plasticity in the hippocampus, prefrontal cortex, and amygdala in response to spatial learning, predator exposure, and stress-induced amnesia.Hippocampus. 2012 Mar;22(3):577-89. doi: 10.1002/hipo.20922. Epub 2011 May 2.

Salim S, Asghar M, Taneja M, Hovatta I, Chugh G, Vollert C, Vu A. Potential Contribution of Oxidative Stress and Inflammation to Anxiety and Hypertension. Brain Res. 2011 Aug 2;1404:63-71. Epub 2011 Jun 16. PubMed PMID: 21704983.

Salim S, Asghar M, Taneja M, Hovatta I, Wu YL, Saha K, Sarraj N, Hite B. Novel role of RGS2 in regulation of antioxidant homeostasis in neuronal cells. FEBS Lett. 2011 May 6;585(9):1375-81. Epub 2011 Apr 16. PubMed PMID: 21510939; PubMed Central PMCID: PMC3108258.

Vollert C, Zagaar M, Hovatta I, Taneja M, Vu A, Dao A, Levine A, Alkadhi K, Salim S. Exercise prevents sleep deprivation-associated anxiety-like behavior in rats: potential role of oxidative stress mechanisms. Behav Brain Res. 2011 Oct 31;224(2):233-40.

Salim S, Asghar M, Taneja M, Hovatta I, Chugh G, Vollert C, Vu A. Potential contribution of oxidative stress and inflammation to anxiety and hypertension. Brain Res. 2011 Aug 2;1404:63-71.

Zoladz PR, Park CR, Halonen JD, Salim S, Alzoubi KH, Srivareerat M, Fleshner M, Alkadhi KA, Diamond DM. Differential expression of molecular markers of synaptic plasticity in the hippocampus, prefrontal cortex, and amygdala in response to spatial learning, predator exposure, and stress-induced amnesia. Hippocampus. 2011 May 2. doi: 10.1002/hipo.20922.

Taneja M, Salim S, Saha K, Happe HK, Qutna N, Petty F, Bylund DB, Eikenburg DC. Differential effects of inescapable stress on locus coeruleus GRK3, alpha2-adrenoceptor and CRF1 receptor levels in learned helpless and non-helpless rats: a potential link to stress resilience. Behav Brain Res. 2011 Aug 1;221(1):25-33.

Srivareerat, M., Tran, T., Salim S, Aleissa, AM., and Alkadhi, KA. Chronic nicotine restores normal A-beta levels and prevents short term memory and E-LTP impairment in A-beta rat model of Alzheimer's disease. Neurobiol Aging 2011 May;32(5):834-44.

Books & Chapters

The role of Grape Powder in Emotional Well-Being and Memory Improvement. Book Chapter, Diet and Demnetia, Elsevier Pubs, 2014.

Alkadhi KA, Salim S, and Alzoubi K. Prevention of Brain Disorders by Nicotine. Book chapter, Natural Products, Springer-Verlag Berlin Heidelberg. 2013.

Principles of Drug Action,Edited by Aditi Marwaha, Thomas Lemke and Samina Salim, Cognella Pub., University Readers Inc. USA

Abstracts and Presentations

Hesong Liu, Fatin Atrooz, Ankita Salvi and Samina Salim. Animal Model of Early Life Stress: Understanding Stress Resilience and Susceptibility,” ASIOA, Houston, TX, January 16, 2017.

Atrooz F, Liu H, and S Salim, 2017. The effect of early life sleep disturbance on rat’s behavior at different life stages, ASIOA, Houston, TX, January 16, 2017.

Ankita Salvi, Gaurav Patki, Hesong Liu, Safiyya Zaidi and Samina Salim. Psychological and Neurobiological Impact of Simulated Vehicle Exhaust Exposure (SVEE) in Rats. ASIOA, Houston, TX, January 17, 2017. (Oral presentation)

Safiyya Zaidi, Hesong Liu, Daniel Valdez, Camila Kochi, Fatin Atrooz, Ankita Salvi Richard A. Bond and Samina Salim. Effectiveness of Beta Blockers in Preventing PTSD-Like Behavior in Rats. ASIOA, Houston, TX, January 16, 2017. (Oral presentation)

Camila Kochi, Safiyya Zaidi, Hesong Liu, Fatin Atrooz, Phoebe Dantoin, Samina Salim. Physical Exercise and Trauma: Insights from an Animal Model. ASIOA, Houston, TX, January 16, 2017

Early Life Exposure to Stress: Insights from a Rat Model. Hesong Liu and Samina Salim. Anxiety and Depression association of America (ADAA) Conference, March 31-April 3, 2016, Philadelphia.

Atrooz F, LiuH, and S Salim, 2016. Early Life Sleep Restriction Induces Behavioral and Cognitive Impairment in Sprague Dawley Rats. Society for Neuroscience meeting, San Diego, California.

Ankita Salvi, Gaurav Patki, Hesong Liu and Samina Salim. Effect of Simulated Vehicle Exhaust Exposure (SVEE) On Behavioral And Cognitive Parameters In Rats. University of Houston annual PPS Research symposium, August 12, 2016.

Hesong Liu, Fatin Atrooz, Ankita Salvi and Samina Salim. Early Life Exposure to Stress: Insights from a Rat Model. University of Houston annual PPS Research symposium, August 12, 2016

Atrooz F, LiuH, and S Salim. 2016, Early Life Repeated Sleep Restriction Induces Behavioral and Cognitive impairments in Sprague-Dawley Rats. Pharmacological and Pharmaceutical Sciences Symposium, University of Houston, Houston, USA.

Safiyya Zaidi, Daniel Valdez, Hesong Liu, Camila Kochi, Phoebe Dantoin, Fatin Atrooz, Ankita Salvi, Richard Bond, and Samina Salim. Protective Effect of Nadolol and Propranolol on PTSD-Like Behavior in Rats. Fourth Annual PPS Symposium held at University of Houston, August 11-12th, 2016.

Safiyya Zaidi, Daniel Valdez, Hesong Liu, Camila Kochi, Phoebe Dantoin, Fatin Atrooz, Ankita Salvi, Richard Bond, and Samina Salim. Protective Effect of Nadolol and Propranolol on PTSD-Like Behavior in Rats. 12th Annual Undergraduate Research Day held at the University of Houston, October 13th, 2016

Behavioral, cognitive and biochemical consequences of witnessing maternal abuse: Insights from an animal model. Hesong Liu, Gaurav Patki, Ankita Salvi, Mathew Kelly and Samina Salim. Experimental Biology, March 29-April 1, 2015, Boston, MS.

Ankita Salvi, Gaurav Patki, Hesong Liu and Samina Salim. Behavioral and biochemical consequences of simulated vehicle exhaust exposure. Annual Meeting of the Society For Neuroscience (SFN), October 17-21, 2015, Chicago, IL.

Solanki N, Patki G, Atrooz F, and Salim S. Grape powder supplementation prevents cognitive, behavioral, and biochemical impairments in the rat model of social stress (2015). Society for Neuroscience, Chicago, IL.

Solanki N, Patki G, Atrooz F, and Salim S. Beneficial effects of grape powder supplement in a rat model of social stress. GRASP, University of Houston, TX, 2015.

Solanki N, Patki G, Atrooz F, and Salim S. Grape powder supplementation prevents and reverses cognitive, behavioral and biochemical impairments in a rat model of social stress. Pharmacological and Pharmaceutical Symposium, Houston, TX.

Salim S, Lui H, Salvi A and Patki G. Witnessing Maternal Abuse during Post-Natal Day 21-27 Induces Depression-Like Behavior in Adult Rats. (2014), American college of Neuropsychopharmacology, Phoenix, Arizona.

Patki G, Salvi A, Liu H, Atrooz F and Salim S. Tempol protects anxiogenic drug induced anxiety-like behavior in rats (2014), Society for Neuroscience, Washington D.C.

Solanki N, Alkadhi I, Atrooz F, Patki G and Salim S. Grape powder supplementation prevents cognitive, behavioral and biochemical impairments in rat model of posttraumatic stress disorder (2014). Society for Neuroscience, Washington D.C.

Salvi A, Patki G, Asghar M and Salim S. Effect of tempol on oxidative stress-induced mitochondrial dysfunction in HT22 cells (2014). 5th World Congress on Targeting Mitochondria, Berlin, Germany.

Kelly M, Liu H, Patki G and Salim S. Coping deficits in post-partum female rats (2014). University of Houston undergraduate research day, Houston.

Liu, H, Salvi A, Alkadhi I, Kelly M, Patki G and Salim S. Post-partum traumatic events trigger severe behavioral deficits in female rats (2014). Pharmacological and Pharmaceutical Symposium, Houston.

Salvi A, Patki G, Liu H, Atrooz F and Salim S. Tempol rescues social defeat-induced behavioral deficits in rats (2014). 2nd Pharmacological and Pharmaceutical Symposium, Houston.

Patki G, Solanki N, Allam F, Alkadhi I and Salim S. Increased anxiety-like behaviors is associated with differential aggression observed in retired breeder Long Evans rats (2014). Experimental Biology, San Diego. Selected for Best Poster Competition.

Salim S, Patki G, Chugh G, Bohat R, Allam F, Jafri F, Saleem M, Asghar M, and Alkadhi K. Grape powder supplementation improves blood pressure, anxiety-like behavior and learning and memory function in ovariectomized rats (2013). Experimental Biology, Boston (20-24 April 2013).

Patki G, Allam F, Bohat R, Jafri F and Salim S. Role of oxidative stress mechanisms in anxiety-like behavior and learning and memory impairment in a rat model of social stress. Experimental Biology, Boston (20-24 April 2013).

Salim S, Patki G, Solanki N, Ansari A, Allam F, Atrooz F, Jannise B and Maturi J. Potential role of histone acetylation in treadmill exercise based rescue of social defeat-induced anxiety and depression-like behaviors, and learning-memory impairment in rats. FASEB, Lucca, Italy. (18-23 August 2013).

Solanki N, Patki G, Atrooz F, Allam F, Ansari A, Jannise B, Maturi J and Salim S. Preventive effect of moderate treadmill exercise on social defeat-associated cognitive, behavioral and biochemical impairments in rats (2013). Society of Neuroscience, San Diego (9-13 November 2013).

Salim S, Patki G, Solanki N, Allam F and Ansari A. A new model for studying effects of witnessing traumatic events in rats. American college of Neuropsychopharmacology, Florida (8-12 December 2013).

Solanki N, Patki G, Ansari A, Allam F, Jannise B, Maturi J, Atrooz F and Salim S. Moderate treadmill exercise rescues social defeat-induced anxiety and depression-like behavior and learning-memory impairment in rats. 1st PPS Symposium. Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, TX (15th August 2013).

Patki G, Solanki N, Allam F, Amber A, Salim S. A new model for studying effects of witnessing traumatic events in rats. 1st PPS Symposium. Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, TX (15th August 2013).

Li L, Patki G, Solanki N, Allam F, Amber A, Salim S, Alkadhi K. Moderate treadmill exercise rescues anxiety and depression-like behavior and memory impairment in a posttraumatic stress model. Research Poster Day. Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, TX (10th October 2013).

Ansari A, Patki G and Salim S. Biochemical changes in the brain in response to social stress and treadmill exercise in rats. Research Poster Day. Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, TX (10th October 2013).

Salim S, Chugh G, Dao A, Asghar M and Alkadhi K. Salt-sensitivity is associated with anxiety (2012). Society of Neuroscience, New Orleans, LA (13-17 October).

Samina Salim, Gaurav Chugh, An Dao, Mohammad Asghar and Karim Alkadhi. Salt sensitivity is associated with anxiety. Society for Neuroscience meeting, 2012.

Samina Salim, Farida Allam, Gaurav Chugh, An Dao, Mohammad Asghar, Manish Taneja, Kaustuv Saha. Protective Effect of Grape Powder On Anxiety-Like Behavior, Blood Pressure and Learning and Memory. , Experimental Biology, San Diego, 2012.

Invited Reviews & Lectures

Reviews

Salim S. Oxidative Stress in Anxiety: Implications for Pharmacotherapy. The American Journal of Integrative Medicine, Vol. 1, No.1, pp.1-2, 2011.

Salim S. Inflammation in Neuropsychiatric Disorders. Advances in Protein Chemistry and Structural Biology.  In press, 2011

Zagaar M, Al-Zoubi K, Alhaider A, Salim S and Alkadhi A. Neurobiology of Disordered Sleep Special Issue of NeuroMolecular Medicine. In press, 2011

Lectures

Selected speaker, Assistant Professor Excellence Speaker Series (Apex) organized by University of Houston faculty senate, April 27, 2016.

Symposium speaker and session chair, Session title: “Stress and Behavior,” Budapest, Hungary, June 7-9, 2016, International Society of Behavioral Neuroscience (IBNS) annual meeting.

Invited speaker, Association of Scientists of Indian Origin (ASIO), Orlando, Florida, January, 2015.

1st Global Conference of Biological Psychiatry, New Delhi, India. Why Persistent Psychological Stress Contributes to Anxiety, Depression and Cognitive Impairment? (September, 2014).

1st Annual Graduate Research and Scholarship Projects (GRaSP) Day prep talk, University of Houston, “IT IS NOT WHAT YOU SAY, IT IS HOW YOU SAY IT”, Facilitated by Samina Salim, 09/12/2014.

National Institute of Environmental Health Sciences (NIEHS) of the National Institutes of Health, UTMB, Galveston, TX 10/30/13.

Biology Colloquium, Department of Biology UH Downtown, TX, 02-15-2013.

Department of Biology and Biochemistry, University of Houston, 03-18-2013.

Basic Medical Sciences College of Osteopathic Medicine of the Pacific Western University of Health Sciences, Pomona, Calif., Oct. 6, 2011

American College of Neuropsychopharmacology (ACNP) annual meeting special panel entitled, ”Oxidative Stress in Psychiatric Disorders: Implications for Pathophysiology and Pharmacotherapy”, Miami, FL, Dec. 5-9, 2010

Department of Pharmacology, College of Pharmacy, University of Toledo, Ohio, June 16, 2009

Department of Pharmaceutical Sciences, Western University of Health Sciences, Pomona, Calif., April 16, 2009

Department of Biomedical Sciences, Marquette University, Milwaukee, Wisc., January 22, 2008

“Emerging Investigators Symposium,” sponsored by Houston Center for Clinical and Translational Science, Houston, Texas, May 21, 2007.

Editorial & Service Appointments

Journal Reviewer

  • Biological Psychiatry
  • Physiology & Behavior
  • Brain Research Bulletin
  • European Neuropsychopharmacology
  • Behavioural Brain Research
  • Psychoneuroendocrinology
  • Bulletin of Environmental Contamination and Toxicology
  • Journal of Biomedicine and Biotechnology
  • Clinical and Experimental Hypertension
  • BMC Biochemistry
  • Journal of Toxicology
  • Advances in Pharmacological Sciences
  • Neuropharmacology
  • British Journal of Nutrition
  • Psychiatry Research
  • Hippocampus
  • PLOS ONE
  • Medicine & Science in Sports & Exercise
  • Current Neuropharmacology
  • European Journal of Pharmacology
  • Scientific Reports, NPG
  • Neuroscience Letters
  • Neuroscience
  • Psychiatry Research
  • Journal of Neuroinflammation
  • Phytomedicine
  • Air Quality, Atmosphere and Health
  • Brain, Behavior and Immunity
  • Journal of Affective Disorders
  • Current Opinion in Behavioral Sciences
  • Journal of the Neurological Sciences
  • Nutrients
  • Progress in Neuropsychopharmacology & Biological Psychiatry
  • Redox Report
  • Journal of Pharmacology Experimental Therapeutics (JPET)

Editorial Board Member

Bulletin of Environmental Contamination and Toxicology

Grant Reviewer

  • Ad hoc member, NIH, NPAS Roster, February 2-3, 2017
  • National Science Foundation (NSF) Graduate Research Fellowship Program (GRFP), January 24 and January 27, 2017
  • Invited reviewer, General Direction for Scientific Research and Health Innovation Grants, Italian Ministry of Health, Italy, December 2016
  • American Association of Colleges of Pharmacy (AACP)’s New Investigator award (NIA) for the Biological Sciences Section, 2016
  • Ad hoc member, NIH, NPAS Roster October 5-7, 2016
  • Ad hoc member, NIH, PMDA Roster June 2-3, 2016
  • National Science Foundation (NSF) Graduate Research Fellowship Program (GRFP), January 11 and January 14, 2016
  • Invited reviewer, General Direction for Scientific Research and Health Innovation Grants, Italian Ministry of Health, Italy, May 2015
  • Ad hoc member, NIH, Neural Basis of Psychopathology, Addictions and Sleep Disorders (NPAS), October 8-9, 2015
  • Ad hoc member, NIH, PMDA Roster October 1-2, 2015
  • Ad hoc member, NIH, Neural Basis of Psychopathology, Addictions and Sleep Disorders (NPAS), May 28-29, 2015
  • Invited Reviewer, Oklahoma Center for the Advancement of Science and Technology (OCAST), Oklahoma City, OK, May 17-18, 2015
  • National Science Foundation (NSF) Graduate Research Fellowship Program (GRFP), January 2015
  • The Netherlands Organisation for Health Research and Development Grants, 2015
  • Scientific Research Support Fund (SRSF), Ministry of Jordan, Amman, Jordan, March 2014
  • Ad hoc member, NIH, PMDA Roster, June 2-3, 2014
  • Ad hoc member, NIH, PMDA Roster, February 6-7, 2014
  • Ad hoc member, NIH, ZRG1 PMDA-J (02), October 11, 2013
  • Ad hoc member, NIH, PMDA Roster, October 10-11, 2013
  • Ad hoc member, NIH, PMDA Roster, June 6-7, 2013
  • Ad hoc member, NIH, Pathophysiological Basis of Mental disorders and Addictions Study Section (PMDA) Roster, February 7-8, 2013
  • AHA Peer Review Meeting, Western States Innovative research Award, 2012
  • American Heart Association (AHA), 2012
  • American Heart Association (AHA), Brain 1 & 3 committee, 2011
  • National Science Foundation (NSF) Graduate Research Fellowship Program (GRFP), 2011
  • University of Houston, Grants to Enhance and Advance Research (GEAR), 2010
  • American Heart Association (AHA), Brain 1 & 3 committee, 2010
  • American Heart Association (AHA), EMIV committee, 2009
  • American Heart Association (AHA), Unified Peer Review, 2008

Affiliations

  • Member, Society For Neuroscience (SFN), 2007-present
  • Member, American Society For Pharmacology and Experimental Therapeutics (ASPET), 2004-present
  • Member, Association of Scientists of Indian Origin (ASIOA), 2007-present
  • Council Member, Association of Scientists of Indian Origin (ASIOA), 2016-present
  • Member, International Society of Behavioral Neuroscience (IBNS), 2015-present
  • Member, Anxiety Disorders Association of America (ADAA)

Available Positions

Positions are available in the laboratory for (1) research technician and (1) post-doctoral fellow to work on an NIMH-funded project investigating role of oxidative stress in anxiety-like behavior in rats using molecular, biochemical, cellular and rodent behavioral approaches. Experience in fluorescent microscopy, brain histochemistry, animal models of anxiety, depression, stress and molecular biology is preferred.

Please send a CV, a brief statement of research interests, and contact information to: Samina Salim at ssalim@uh.edu.