Skip to main content

Profile: Hua Chen

chen-hua.jpg
Hua Chen, M.D., Ph.D.
Associate Professor of Pharmaceutical Health Outcomes and Policy

Health 2
University of Houston College of Pharmacy
4849 Calhoun Road, Room 4048
Houston, TX 77204-5047

832-842-8355
hchen20@uh.edu

Education

Ph.D. in Pharmacy Care Administration, University of Georgia College of Pharmacy, Athens, GA

Master of Science in Pharmacology, Hunan Medical University, China

Medical Degree in General Medicine, Hunan Medical University, China

Awards and Honors

  • Best poster presentation award at Houston Medication Safety Symposium 2017.
  • A silver medal winning abstract at the AMCP Managed Care & Specialty Pharmacy Annual Meeting, March 27-30, 2017. Denver, Colorado.
  • Best poster award at ISPOR 22st Annual International Meeting, May 20-24, 2017. Boston, MA.
  • Best podium presentation award at ISPOR 18th Annual International Meeting, , May 18-23, 2013. New Orleans, LA, USA.
  • 5) Best podium presentation award at ISPOR 17th Annual International Meeting, June 2-6, 2012. Washington, D.C., USA.
  • Best New Investigator Podium Presentation Award, ISPOR 11th Annual European Congress,  November 8-11, 2008. Athens, Greece.
  • Best Poster Presentation Award, ISPOR 13th Annual International Meeting, May 3-7, 2008. Toronto, ON, Canada.
  • First Place Poster Presentation Award, 8th Annual Health Services and Outcomes Research Conference (Kelsey Research Foundation), December 2007. Houston, TX.

Research Grants (External)

Does Access to Patient Centered Medical Home reduce Racial and Ethnic Disparities in the care for Pediatric Major Depressive Disorders?
Principal Investigator: Hua Chen
Funding Agency: Agency for Healthcare Research and Quality (AHRQ)
Time period: September 2017 - August 2019

Drug utilization and medication adherence among patients with Hepatic Encephalopathy enrolled in a Medicare advantage plan and predictors of hospital readmission.
Principal Investigators: Susan Abughosh, Hua Chen
Funding Agency: Valeant Pharmaceuticals
Time Period: June 2018 - May 2019

Safety profile of antimuscaringics in elderly dementia patients.
Principal Investigator: Rajender Aparasu
Co-Investigator: Hua Chen
Funding Agency: NIH
Time Period: July 2017 - June 2019

Anticholinergics and Cognitive Decline in the Elderly with Depression.
Principal Investigator: Rajender Aparasu
Co-Investigator: Hua Chen
Funding Agengy: Agency for Healthcare Research and Quality (AHRQ)
Time Period: August 2012 - July 2017

HHS Contract under the SAMHA Strategic Prevention Framework for Prescription Drugs Grant Program
Principal Investigator: Marc Fleming
Co-Investigator: Hua Chen
Funding Agency: Texas Health and Human Services Commission
Time Period: February 2017 - August 2017

Risk of Thrombosis and Bleeding in Patients on Warfarin or Apixaban (Eliquis) and Concomitant Anti-arrhythmic Medications
Principal Investigator: Matthew Wanat
Co-Investigator: Hua Chen
Funding Agency: Bristol-Myers Squibb/Pfizer
Time Period: January 2017 - January 2019

The definition, utilization, and development of long term psychotropic polypharmacy in children and adolescents.
Principal Investigator: Hua Chen
Funding Agency: PHRMA Foundation
Time period: January 2010 - December 2012

The impact of the FDA antidepressant black box warning on psychiatric practice.
Principal Investigator: Hua Chen
Co-Investigators: Rajender Aparasu, Michael Johnson
Funding Agency: Agency for Healthcare Research and Quality (AHRQ)
Time period: March 2007 – June 2009

The impact of the FDA antidepressant black box warning on the utilization of psychotherapy, psychotropic medications, and antidepressant follow-up care among children and adolescents.
Principal Investigator: Hua Chen
Funding Agency: American Association of Colleges of Pharmacy (AACP)
Time period: December 2006 – December 2007

Outcomes of Angiogenesis Receptor Blocker Use for Heart Failure in the Elderly
Principal Investigator: Michael Johnson
Co-Investigators: Hua Chen, Robert Morgan
Funding Agency: Agency for Healthcare Research and Quality (AHRQ)
Time period: July 2008 – June 2010

Impact of Atypical Antipsychotic Use on Health Care Utilization in the Elderly
Principal Investigator: Rajender Aparasu
Co-Investigator: Hua Chen
Funding Agency: Agency for Healthcare Research and Quality (AHRQ)
Time period: March 2008 – August 2010

Research Grants (Internal)

Building a Data Platform to Assess the Impact of the Patient Centered Medical Home (PCMH) on Disparities in Pediatric Mental Health Care.
Principal Investigator: Hua Chen
Funding Agency: University of Houston, Grants to Enhance and Advance Research (GEAR) Program
Time Period: June 2017 - May 2018

Adverse drug events associated with the off-label uses of the second generation antipsychotic, antidepressant and anticonvulsant medications: An analysis of Food and Drug Administration MedWatch database.
Principal Investigator: Hua Chen
Funding Agency: University of Houston, New Faculty Research Award Program
Time period: February 2006 – August 2006

Selected Publications

Physician care coordination and the use of psychotropic polypharmacy in the management of pediatric mental disorders. Medhekar R, Fujimoto K, Aparasu RR, Bhatara VS, Johnson ML, Alonzo JP, Schwarzwald HL, Chen H. J Manag Care Spec Pharm. 2019 Jan;25(1):29-38. doi: 10.18553/jmcp.2019.25.1.029. PubMed PMID: 30589632.

Racial/ethnic differences in the treatment of adolescent major depressive disorders (MDD) across healthcare providers participating in the medicaid program. Yucel A, Essien EJ, Sanyal S, Mgbere O, Aparasu RR, Bhatara VS, Alonzo JP, Chen H. J Affect Disord. 2018 Aug 1;235:155-161. doi: 10.1016/j.jad.2018.04.045. Epub 2018 Apr 6. PubMed PMID: 29656260.

Care provision and prescribing practices of physicians treating children and adolescents With ADHD. Patel A, Medhekar R, Ochoa-Perez M, Aparasu RR, Chan W, Sherer JT, Alonzo J, Chen H. Psychiatr Serv. 2017 Jul 1;68(7):681-688. doi: 10.1176/appi.ps.201600130. Epub 2017 Feb 15. PubMed PMID: 28196459.

Effect of psychopharmacotherapy on Body Mass Index among children and adolescents with bipolar disorders. Patel A, Chan W, Aparasu RR, Ochoa-Perez M, Sherer JT, Medhekar R, Chen H. J Child Adolesc Psychopharmacol. 2017 May;27(4):349-358. doi: 10.1089/cap.2016.0133. Epub 2017 Apr 19. PubMed PMID: 28422528.

Risk of manic switch associated with antidepressant therapy in pediatric bipolar depression. Bhowmik D, Aparasu RR, Rajan SS, Sherer JT, Ochoa-Perez M, Chen H. J Child Adolesc Psychopharmacol. 2014 Dec;24(10):551-61. doi: 10.1089/cap.2014.0028. PubMed PMID: 25470655.

The utilization of psychopharmacological treatment and medication adherence among Medicaid enrolled children and adolescents with bipolar depression. Bhowmik D, Aparasu RR, Rajan SS, Sherer JT, Ochoa-Perez M, Chen H. J Affect Disord. 2013 Sep 5;150(2):424-9. doi: 10.1016/j.jad.2013.04.034. PubMed PMID: 23747210.

The definition and prevalence of pediatric psychotropic polypharmacy. Chen H, Patel A, Sherer J, Aparasu R. Psychiatr Serv. 2011 Dec;62(12):1450-5. doi: 10.1176/appi.ps.000642011. PubMed PMID: 22193792.

The impact of Medicare Part D on psychotropic utilization and financial burden for community-based seniors. Chen H, Nwangwu A, Aparasu R, Essien E, Sun S, Lee K. Psychiatr Serv. 2008 Oct;59(10):1191-7. doi: 10.1176/appi.ps.59.10.1191. PubMed PMID: 18832506.

Off-label use of antidepressant, anticonvulsant, and antipsychotic medications among Georgia medicaid enrollees in 2001. Chen H, Reeves JH, Fincham JE, Kennedy WK, Dorfman JH, Martin BC. J Clin Psychiatry. 2006 Jun;67(6):972-82. PubMed PMID: 16848658.

An epidemiological investigation of off-label anticonvulsant drug use in the Georgia Medicaid population. Chen H, Deshpande AD, Jiang R, Martin BC. Pharmacoepidemiol Drug Saf. 2005 Sep;14(9):629-38. PubMed PMID: 15597329.

For complete list of publications and presentations, please see Google Scholar.

Selected Conference Presentations

Upadhyay N, Rowan JP, Fleming ML, Aparasu RR, Balkrishnan R, and Chen H. Can Primary and Behavioral Health Integration Reduce Racial/ethnic Disparities in the Identification of Pediatric Mental Disorders? AACAP's 65th Annual Meeting in Seattle, Washington, October 22-27, 2018.

Upadhyay N, Rowan JP, Fleming ML, Aparasu RR, Balkrishnan R, and Chen H. Geographic Access to Primary Care Provider and Behavioral Disorder Screening: Variations Across Race/Ethnicity. AACAP's 65th Annual Meeting in Seattle, Washington, October 22-27, 2018.

Yucel A, Sanyal S, Essien EJ, Mgbere O, Aparasu RR, Bhatara V, Alonzo J, Chen H. Racial/Ethnic Differences In The Treatment Of Adolescent Major Depressive Disorders (MDD) Across Healthcare Providers Participating In The Medicaid Program. ISPOR 23rd Annual International Meeting, Baltimore, MD, May 19-23, 2018.

Medhekar R, Fujimoto K, Aparasu R, Bhatara V, Johnson M, Alonzo J, Schwarzwald H, Chen H. Association Between Physician Care Coordination and the Use of Psychotropic Polypharmacy in the Management of Pediatric Mental Disorders. AMCP Managed Care & Specialty Pharmacy Annual Meeting 2018,Denver, Colorado, March 27-30, 2018

Medhekar R, Fujimoto K, Aparasu R, Bhatara V, Johnson M, Alonzo J, Schwarzwald H, Chen H. Physician Peer-Influence on Prescribing Psychotropic Polypharmacy in the Treatment of Children and Adolescents With Mental Disorders. AACAP's 64th Annual Meeting in Washington, DC, October 23-28, 2017.

Medhekar R, Fujimoto K, Aparasu RR, Bhatara V, Johnson ML, Alonzo J, Schwarzwald H, Chen H. Psychotropic Polypharmacy In The Treatment Of Children And Adolescents With Mental Disorders: Prevalence And Determinants. ISPOR 22nd Annual International Meeting, Boston, MA, May 20-24, 2017,

For complete list of publications and presentations, please see Google Scholar.