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Faculty Profile

Kathleen GajewskiKathleen Gajewski

Research Assistant Professor and Biology & Biochemistry Imaging Core Manager
Department of Biology and Biochemistry

Office: Science & Research 2, 328A
Contact: kmgajewski@uh.edu - (713) 743 3796

Education: Ph.D., Rice University

Website

Dr. Kathleen Gajewski’s main interest is the running of the Biology and Biochemistry Imaging Core.

Her goals are to:

  • Train research personnel in the use of confocal microscopes, through one-on-one training and the BIOL6222 Optical Methods in Biology class
  • Help researchers plan, conduct and troubleshoot imaging experiments
  • Expand Core function and services by obtaining additional imaging instruments.
  • Schroeder MC, Chen CL, Gajewski K, Halder G. A non-cell-autonomous tumor suppressor role for Stat in eliminating oncogenic scribble cells. Oncogene. 2013; 32(38):4471-9.
  • Gajewski KM and Schulz RA. CF2 represses actin 88F gene expression and maintains filament balance during indirect flight muscle development in Drosophila. PLoS One. 2010; 5(5): e1071
  • Chen CL, Gajewski KM, Hamaratoglu F, Bossuyt W, Sansores-Garcia L, Tao C, Halder G. The apical-basal cell polarity determinant Crumbs regulates Hippo signaling in Drosophila. Proc Natl Acad Sci USA. 2010; 107: 15810-15815.
  • Hamaratoglu F, Gajewski K, Sansores-Garcia L, Morrison C, Tao C, Halder G. The Hippo tumor-suppressor pathway regulates apical-domain size in parallel to tissue growth. J Cell Sci. 2009; 122(Pt 14): 2351-2359.
  • Tokusumi T, Russell M, Gajewski K, Fossett N, Schulz RA. U-shaped protein domains required for repression of cardiac gene expression in Drosophila. Differentiation. 2007; 75:166-174.
  • Tao Y, Wang J, Tokusumi T, Gajewski K, Schulz RA. Requirement of the LIM homeodomain transcription factor tailup for normal heart and hematopoietic organ formation in Drosophila melanogaster. Mol Cell Biol. 2007; 27:3962-3969.
  • Gajewski KM, Sorrentino RP, Lee JH, Zhang Q, Russell M, Schulz RA. Identification of a crystal cell-specific enhancer of the black cells prophenoloxidase gene in Drosophila. Genesis. 2007; 45: 200-227.
  • Gajewski KM, Wang J, Schulz RA. Calcineurin function is required for myofilament formation and troponin I isoform transition in Drosophila indirect flight muscle. Dev Biol. 2006; 289:17-29.
  • Muratoglu S, Garratt B, Hyman K, Gajewski K, Schulz RA, Fossett N. Regulation of Drosophila Friend of GATA gene, u-shaped, during hematopoiesis: A direct role for Serpent and Lozenge. Dev Biol. 2006; 296 :561-69.
  • Choi CY, Kim YH, Kim YO, Park SJ, Kim EA, Riemenschneider W, Gajewski K, Schulz RA, Kim Y. Phosphorylation by the DHIPK2 Protein Kinase Modulates the Corepressor Activity of Groucho. J Biol Chem. 2005; 280:21427-36.
  • Wang J, Tao Y, Reim I, Gajewski K, Frasch M, Schulz RA. Expression, regulation, and requirement of the toll transmembrane protein during dorsal vessel formation in Drosophila melanogaster. Mol Cell Biol. 2005; 25: 4200-10.
  • Gajewski K, Wang J, Molkentin J, Chen EH, Olson EN, and Schulz RA. Requirement of the calcineurin subunit gene CanB2 for indirect flight muscle formation in Drosophila. Proc Natl Acad Sci U S A., 2003; 100, 1040-5.
  • Fossett N, Hyman K, Gajewski K, Orkin SH, and Schulz RA. Combinatorial interactions of Serpent, Lozenge, and U-shaped regulate crystal cell lineage commitment during Drosophila hematopoiesis. Proc Natl Acad Sci, 2003; 100: 11451-6.
  • Lo PC, Skeath JB, Gajewski K, Schulz RA, Frasch M. Homeotic genes autonomously specify the anteroposterior subdivision of the Drosophila dorsal vessel into aorta and heart. Dev. Biol. 2002; 251, 307-19.
  • Gajewski K, Zhang Q, Choi CY, Fossett N, Dang A, Kim YH, Kim Y, Schulz RA. Pannier is a transcriptional target and partner of Tinman during Drosophila cardiogenesis. Dev Biol 2001; 233(2):425-36.
  • Fossett N, Tevosian SG, Gajewski K, Zhang Q, Orkin SH, Schulz RA. The Friend of GATA proteins U-shaped, FOG-1, and FOG-2 function as negative regulators of blood, heart, and eye development in Drosophila. Proc Natl Acad Sci U S A. 2001; 98(13):7342-7.
  • Markesich DC, Gajewski KM, Nazimiec ME, Beckingham K. bicaudal encodes the Drosophila beta NAC homolog, a component of the ribosomal translational machinery. Development 2000; 127(3):559-72.
  • Fossett N, Zhang Q, Gajewski K, Choi CY, Kim Y, Schulz RA. The multitype zinc-finger protein U-shaped functions in heart cell specification in the Drosophila embryo. Proc Natl Acad Sci U S A 2000; 97(13):7348-53.
  • Gajewski K, Choi CY, Kim Y, Schulz RA. Genetically distinct cardial cells within the Drosophila heart. Genesis 2000; 28(1):36-43.
  • Stitzinger SM, Pellicena-Palle A, Albrecht EB, Gajewski KM, Beckingham KM, Salz HK. Mutations in the predicted aspartyl tRNA synthetase of Drosophila are lethal and function as dosage-sensitive maternal modifiers of the sex determination gene Sex-lethal. Mol Gen Genet 1999; 261(1):142-51.
  • Gajewski K, K, Fossett N, Molkentin JD, Schulz RA. The zinc finger proteins Pannier and GATA4 function as cardiogenic factors in Drosophila. Development 1999; 126(24):5679-88.
  • Kremser T, Gajewski K, Schulz RA, Renkawitz-Pohl R. Tinman regulates the transcription of the beta3 tubulin gene (betaTub60D) in the dorsal vessel of Drosophila. Dev Biol 1999; 216(1):327-39.
  • Schulz RA, Gajewski K. Ventral neuroblasts and the heartless FGF receptor are required for muscle founder cell specification in Drosophila. Oncogene 1999; 18(48):6818-23.
  • Gajewski K, Kim Y, Choi CY, Schulz RA. Combinatorial control of Drosophila mef2 gene expression in cardiac and somatic muscle cell lineages. Dev Genes Evol 1998; 208(7):382-92.
  • Gajewski K, Kim Y, Lee YM, Olson EN, Schulz RA. D-mef2 is a target for Tinman activation during Drosophila heart development. EMBO J 1997; 16(3):515-22.
  • Gajewski KM, Schulz RA. Requirement of the ETS domain transcription factor D-ELG for egg chamber patterning and development during Drosophila oogenesis. Oncogene 1995; 11(6):1033-40.