Natural Science and Mathematics
About the College
Academic Regulations
Admission
Requirements
Courses
BCHS Courses
Degrees Offered
Faculty
College of Natural Science and Mathematics
Courses: Biochemical and Biophysical Sciences (BCHS)
6113: Graduate Biochemistry Seminar
Cr. 1. (1-0). Prerequisite: graduate standing in the Department of Biology and Biochemistry. May be repeated for credit. Seminars presented by students, faculty or outside speakers on current research or current biochemical literature.
6125: Seminar in Nucleic Acids
Cr. 1. (1-0). Presentations and discussion on current topics in nucleic acids and nucleic acid-protein interactions.
6198:6298:6398:6498:6598: Special Problems
Cr. 1-5 per semester. Prerequisites: consent of instructor and approval of chair.
6199:6299:6399:6699:7399:7699: Master's Thesis
Cr. 1, 2, 3, or 6 per semester.
6201: Methods in Molecular Biology
Cr. 2. (2-0). Prerequisites: BCHS 3305 and
BIOL 4320 or
BCHS 4306 or equivalents or consent of instructor. Current methods and techniques in molecular biology. Bacterial host strains, expression systems, mutagenesis, DNA library construction and screening, DNA mapping and sequencing and polymerase chain reaction methods.
6203: Enzyme Mechanisms
Cr. 2. (2-0). Prerequisites:
BCHS 3305 or equivalent and consent of instructor. Principles and methods for the evaluation of enzyme reaction mechanisms, emphasizing established and newly developed biochemical, biophysical and molecular biological approaches.
6204: Elements of Protein Structure
Cr. 2. (2-0). Prerequisites:
BCHS 3304 or equivalent and consent of instructor. Taxonomy of protein structure with illustration of the common families of protein structure as well as simple protein structural motifs. Examples taken from the crystallographic and NMR literature.
6205: Cell Signaling
Cr. 2. (2-0). Prerequisites:
BCHS 3305 or equivalent and consent of instructor. Biochemistry of cellular responses to environmental signals at the molecular level.
6206: Molecular Modeling of Biological Macromolecules
Cr. 2. (2-2). Prerequisites:
BCHS 3304 and
CHEM 4370 or
4373 or equivalents or consent of the instructor. Advanced computer-based molecular modeling methods, with emphasis on their practical aspects and limitations. Individual research projects using UNIX-based Silicon Graphics computers.
6208: Biochemistry of Organelles
Cr. 2. (2-0). Prerequisites:
BCHS 3305 or equivalent and consent of instructor. Organization of mitochondrial and chloroplast membranes. Biochemical and biophysical aspects of electron transfer in photosynthetic organelles. Molecular organization of genes and proteins involved in biochemical energy transduction.
6209: Protein Biosynthesis
Cr. 2. (2-0). Prerequisite:
BCHS 3304. Aspects of protein synthesis including ribosome structure, ribosomal RNA structure and function, translation inhibitors, identification of tRNAs, and involvement of tRNA in coding/decoding.
6210: Mobile DNA and Genome Fluidity
Cr. 2. (2-0). Prerequisites:
BIOL 3301 and
BIOL 4320 or
BCHS 4306 or equivalents or consent of instructor. Mechanisms of transposition and recombination by DNA elements.
6216: Biological Membranes
Cr. 2. (2-0). (Also BIOL 6216). Prerequisite: consent of instructor. Structure, metabolism and biological interactions of membrane components. Molecular mechanisms of membrane phenomena.
6217: Molecular Mechanisms of Infectious Disease
Cr. 2. (2-0). Host-pathogen interactions, including mechanisms of invasion and intracellular survival. Regulation of virulence gene expression. Host responses and their manipulation by select pathogens. Current approaches for investigating pathogenesis, engineering bacterial toxins, and designing vaccines and antibiotics.
6218: Molecular Mechanisms of Host-Pathogen Interactions
Cr. 2. (2-0). Prerequisites:
BIOL 2333 and
BIOL 4374 and
BCHS 3304 or equivalents or consent of instructor. Molecular basis of interactions between microbial pathogens and the host immune system. Pathogen molecular mimicry, host response modulation, and design and construction of vaccines. Contemporary approaches for experimental investigation of host-pathogen interactions.
6219: Cell Biology of Disease and Immunity
Cr. 2. (2-0). Prerequisites:
BIOL 2333 and
4374 and
BCHS 3304 or equivalents or consent of instructor. Fundamental cellular processes in disease and immunity, including current experimental techniques. Molecular and cellular mechanisms of exploitation of host functions by microbial pathogens. Cellular and mucosal immunity.
6226: Enzyme Catalysis and Kinetics
Cr. 2. (2-0). Prerequisites:
BCHS 3305 or equivalent and graduate standing or consent of instructor. Principles of enzymatic catalysis. Methods and principles of enzyme kinetic analysis.
6227: Membranes and Signal Transduction
Cr. 2. (2-0). Prerequisites:
BCHS 3305 or equivalent and graduate standing or consent of instructor. Membrane biochemistry: metabolism, properties, and structures of membrane lipids; biochemistry of membrane proteins; structure and composition; physical techniques for study; lateral and transverse asymmetry; electrophysiological properties; permeability and partitioning; pores, channels, and transporters; signal transduction.
6228: Advanced Nucleic Acids
Cr. 2. (2-0). Prerequisites:
BCHS 4306 and graduate standing or consent of instructor. Nucleic acid structure, function, and interactions with proteins.
6229: Protein Structure and Function
Cr. 2. (2-0). Prerequisites:
BCHS 3305 or equivalent and graduate standing or consent of instructor. Protein structure/function relationships as exemplified in current structural biology literature.
6230: Graduate Biochemistry Laboratory Rotation I
Cr. 2. (0-6). Prerequisites:
BCHS 3305 and
BCHS 3201 or consent of instructor. Instruction in contemporary concepts and research methodology in several areas of biochemistry.
6231: Graduate Biochemistry Laboratory Rotation II
Cr. 2. (0-6). Prerequisite:
BCHS 6230. Instruction in contemporary concepts and research methodology in several areas of biochemistry.
6232: Advanced Molecular Microbiolgoy
Cr. 2. (2-0). Prerequisite:
BIOL
2333 and BIOL
3304, or consent of instructor. (also BIOL 6232) Mechanisms of fundamental processes in microbial molecular biology. Current literature and experimental techniques.
6233: Avanced Microbial Physiology
Cr. 2. (2-0). Prerequisite:
BIOL
2333 and BIOL
3304, or consent of instructor. (also BIOL 6233) Molecular and cellular mechanisms of fundamental processes in microbial physiology. Current literature and experimental techniques.
6297: Selected Topics in Biochemical and Biophysical Sciences
Cr. 2. (2-0). Prerequisite: consent of instructor. May be repeated for credit when topics vary.
6324:Bioinformatics for Biologists
Cr. 3. (3-0). Prerequisites:
Graduate standing; BIOL 3306
or consent of instructor. Computer-assisted analyses of molecular data including data retrieval, database
usage, sequence alignment, gene identification, phylogenetics, genomics, and proteomics. Individually designed
research projects uses bioinformatic methods.
8198:8298:8398:8498:8598: Doctoral Research
Cr. 1-5 per semester. Prerequisites: consent of instructor and approval of chair.
8199:8299:8399:8699:8999: Doctoral Dissertation
Cr. 1-9 per semester.
College of Natural Science and Mathematics
Courses: Biochemical and Biophysical Sciences (BCHS)
6113: Graduate Biochemistry SeminarCr. 1. (1-0). Prerequisite: graduate standing in the Department of Biology and Biochemistry. May be repeated for credit. Seminars presented by students, faculty or outside speakers on current research or current biochemical literature.
6125: Seminar in Nucleic Acids
Cr. 1. (1-0). Presentations and discussion on current topics in nucleic acids and nucleic acid-protein interactions.
6198:6298:6398:6498:6598: Special Problems
Cr. 1-5 per semester. Prerequisites: consent of instructor and approval of chair.
6199:6299:6399:6699:7399:7699: Master's Thesis
Cr. 1, 2, 3, or 6 per semester.
6201: Methods in Molecular Biology
Cr. 2. (2-0). Prerequisites: BCHS 3305 and
BIOL 4320 or
BCHS 4306 or equivalents or consent of instructor. Current methods and techniques in molecular biology. Bacterial host strains, expression systems, mutagenesis, DNA library construction and screening, DNA mapping and sequencing and polymerase chain reaction methods.
6203: Enzyme Mechanisms
Cr. 2. (2-0). Prerequisites:
BCHS 3305 or equivalent and consent of instructor. Principles and methods for the evaluation of enzyme reaction mechanisms, emphasizing established and newly developed biochemical, biophysical and molecular biological approaches.
6204: Elements of Protein Structure
Cr. 2. (2-0). Prerequisites:
BCHS 3304 or equivalent and consent of instructor. Taxonomy of protein structure with illustration of the common families of protein structure as well as simple protein structural motifs. Examples taken from the crystallographic and NMR literature.
6205: Cell Signaling
Cr. 2. (2-0). Prerequisites:
BCHS 3305 or equivalent and consent of instructor. Biochemistry of cellular responses to environmental signals at the molecular level.
6206: Molecular Modeling of Biological Macromolecules
Cr. 2. (2-2). Prerequisites:
BCHS 3304 and
CHEM 4370 or
4373 or equivalents or consent of the instructor. Advanced computer-based molecular modeling methods, with emphasis on their practical aspects and limitations. Individual research projects using UNIX-based Silicon Graphics computers.
6208: Biochemistry of Organelles
Cr. 2. (2-0). Prerequisites:
BCHS 3305 or equivalent and consent of instructor. Organization of mitochondrial and chloroplast membranes. Biochemical and biophysical aspects of electron transfer in photosynthetic organelles. Molecular organization of genes and proteins involved in biochemical energy transduction.
6209: Protein Biosynthesis
Cr. 2. (2-0). Prerequisite:
BCHS 3304. Aspects of protein synthesis including ribosome structure, ribosomal RNA structure and function, translation inhibitors, identification of tRNAs, and involvement of tRNA in coding/decoding.
6210: Mobile DNA and Genome Fluidity
Cr. 2. (2-0). Prerequisites:
BIOL 3301 and
BIOL 4320 or
BCHS 4306 or equivalents or consent of instructor. Mechanisms of transposition and recombination by DNA elements.
6216: Biological Membranes
Cr. 2. (2-0). (Also BIOL 6216). Prerequisite: consent of instructor. Structure, metabolism and biological interactions of membrane components. Molecular mechanisms of membrane phenomena.
6217: Molecular Mechanisms of Infectious Disease
Cr. 2. (2-0). Host-pathogen interactions, including mechanisms of invasion and intracellular survival. Regulation of virulence gene expression. Host responses and their manipulation by select pathogens. Current approaches for investigating pathogenesis, engineering bacterial toxins, and designing vaccines and antibiotics.
6218: Molecular Mechanisms of Host-Pathogen Interactions
Cr. 2. (2-0). Prerequisites:
BIOL 2333 and
BIOL 4374 and
BCHS 3304 or equivalents or consent of instructor. Molecular basis of interactions between microbial pathogens and the host immune system. Pathogen molecular mimicry, host response modulation, and design and construction of vaccines. Contemporary approaches for experimental investigation of host-pathogen interactions.
6219: Cell Biology of Disease and Immunity
Cr. 2. (2-0). Prerequisites:
BIOL 2333 and
4374 and
BCHS 3304 or equivalents or consent of instructor. Fundamental cellular processes in disease and immunity, including current experimental techniques. Molecular and cellular mechanisms of exploitation of host functions by microbial pathogens. Cellular and mucosal immunity.
6226: Enzyme Catalysis and Kinetics
Cr. 2. (2-0). Prerequisites:
BCHS 3305 or equivalent and graduate standing or consent of instructor. Principles of enzymatic catalysis. Methods and principles of enzyme kinetic analysis.
6227: Membranes and Signal Transduction
Cr. 2. (2-0). Prerequisites:
BCHS 3305 or equivalent and graduate standing or consent of instructor. Membrane biochemistry: metabolism, properties, and structures of membrane lipids; biochemistry of membrane proteins; structure and composition; physical techniques for study; lateral and transverse asymmetry; electrophysiological properties; permeability and partitioning; pores, channels, and transporters; signal transduction.
6228: Advanced Nucleic Acids
Cr. 2. (2-0). Prerequisites:
BCHS 4306 and graduate standing or consent of instructor. Nucleic acid structure, function, and interactions with proteins.
6229: Protein Structure and Function
Cr. 2. (2-0). Prerequisites:
BCHS 3305 or equivalent and graduate standing or consent of instructor. Protein structure/function relationships as exemplified in current structural biology literature.
6230: Graduate Biochemistry Laboratory Rotation I
Cr. 2. (0-6). Prerequisites:
BCHS 3305 and
BCHS 3201 or consent of instructor. Instruction in contemporary concepts and research methodology in several areas of biochemistry.
6231: Graduate Biochemistry Laboratory Rotation II
Cr. 2. (0-6). Prerequisite:
BCHS 6230. Instruction in contemporary concepts and research methodology in several areas of biochemistry.
6232: Advanced Molecular Microbiolgoy
Cr. 2. (2-0). Prerequisite:
BIOL
2333 and BIOL
3304, or consent of instructor. (also BIOL 6232) Mechanisms of fundamental processes in microbial molecular biology. Current literature and experimental techniques.
6233: Avanced Microbial Physiology
Cr. 2. (2-0). Prerequisite:
BIOL
2333 and BIOL
3304, or consent of instructor. (also BIOL 6233) Molecular and cellular mechanisms of fundamental processes in microbial physiology. Current literature and experimental techniques.
6297: Selected Topics in Biochemical and Biophysical Sciences
Cr. 2. (2-0). Prerequisite: consent of instructor. May be repeated for credit when topics vary.
6324:Bioinformatics for Biologists
Cr. 3. (3-0). Prerequisites:
Graduate standing; BIOL 3306
or consent of instructor. Computer-assisted analyses of molecular data including data retrieval, database
usage, sequence alignment, gene identification, phylogenetics, genomics, and proteomics. Individually designed
research projects uses bioinformatic methods.
8198:8298:8398:8498:8598: Doctoral Research
Cr. 1-5 per semester. Prerequisites: consent of instructor and approval of chair.
8199:8299:8399:8699:8999: Doctoral Dissertation
Cr. 1-9 per semester.