Bacterial mutations, the misuse of antibiotics, and the lack of new medications are making the successful treatment of infections with antibiotics more problematic with each passing day—but not for long. Mike Nikolaou, professor of chemical and biomolecular engineering, and Vincent Tam, assistant professor of pharmacy, are devising a method to speed up the development of new antibiotics and to prescribe them in ways that help prevent bacteria from becoming resistant to them. Funded by a National Science Foundation grant, Nikolaou and Tam are developing a computerized modeling system that focuses on potential medications’ dosing regimens and reveals which regimens are most likely to be effective in combating infection and which are not worth pursuing. Drug companies can then focus actual, real-world tests on the best regimens—eliminating tens of thousands of lab experiments. This method can eventually cut the development time of new antibiotics, which typically lasts for more than a decade.