Dr. LaVoy studies the impact of physical and psychological stressors on immune health, with a focus on neuroendocrine-immune interactions. Ongoing projects include investigating whether improving fitness can improve viral control, identifying processes underlying exercise-induced improvements in immune function, and exploring the connection between neural pathways and immunity following exercise. By furthering our understanding of the immune system, this research will improve the quality of life of patients suffering from cancer and inflammation-related diseases.
Recent Publications and Research Activity
LaVoy, E.C., Hussain, M., Reed, J. Kunz, H., Pistillo, M., Bigley, A. and R. J. Simpson. (2017) T-cell redeployment and intracellular cytokine expression following exercise: effects of exercise intensity and cytomegalovirus infection. Physiology Reports, 5 (1)
LaVoy E.C., Fagundes C.P., and R. Dantzer. (2016) Exercise, inflammation, and fatigue in cancer survivors. Exercise Immunology Review, 22 82-93
LaVoy EC, Bollard CM, Hanley PJ, Blaney JW, O’Connor DP, Bosch JA, Simpson RJ. (2015) A single bout of dynamic exercise enhances the expansion of MAGE-A4 and PRAME-specific cytotoxic T-cells from healthy adults. Exerc Immunol Rev, 21,144-53.
LaVoy EC, Bollard CM, Hanley PJ, O’Connor DP, Lowder TW, Bosch JA, Simpson RJ. (2015) A Single Bout of Dynamic Exercise by Healthy Adults Enhances the Generation of Monocyte-Derived-Dendritic Cells. Cellular Immunology 295, 52-59.
LaVoy, E.C., Bigley, A.B., Spielmann, G., Rector, J.L., Morrison, M.R., O’Connor, D.P. and R.J. Simpson. (2014) CMV amplifies T-cell redeployment to acute exercise independently of HSV-1 serostatus. Medicine and Science in Sports and Exercise, 46, 257-267.
Spielmann, G. Bollard, C.M., Bigley, A.B., Hanley, P.J., Blaney, J.W., LaVoy, E.C., Pircher, H. and R.J. Simpson. (2014) The effects of age and latent cytomegalovirus infection on the redeployment of CD8+ T cell subsets in response to acute exercise in humans. Brain Behavior and Immunity, 39, 142-151.
LaVoy, E.C., Nieman, D.C., Henson, D.A., Shanely, R.A., Knab, A.M., Cialdella-Kam, L. and R.J. Simpson. (2013) Latent cytomegalovirus infection does not alter innate immune function in response to a 75-km cycling time trial. Eurpoean Journal of Applied Physiology, 113, 2629-2635.
LaVoy, E.C., Bosch, J.A., Lowder, T.W. and R.J. Simpson. (2013) Acute aerobic exercise in humans increases cytokine expression in CD27- but not CD27+ CD8+ T-cells. Brain Behavior and Immunity, 27, 54-62.
LaVoy, E.C., McFarlin, B.K. and R.J. Simpson RJ. (2011) Immune responses to exercising in a cold environment. Wilderness and Environmental Medicine 22, 343-351
Bigley, A.B., Spielmann, G., LaVoy, E.C. and R.J. Simpson. (2013) Can exercise-related improvements in immunity influence cancer incidence and prognosis in the elderly? Maturitas,76, 51-56.
Pistillo, M., Bigley, A.B., Spielmann, G., LaVoy, E.C., Morrison, M.R., Rahman, M. and R.J. Simpson. (2013) The effects of age and viral serology on gd T-cell numbers and exercise responsiveness in humans. Cellular Immunology, 284, 91-97.
Simpson, R.J., Lowder, T.W., Spielmann, G., Bigley, A.B., LaVoy, E.C. and H. Kunz. (2012) Exercise and the aging immune system. Ageing Research Reviews, 11, 404-420.
B.S. in Biology at Northern Michigan University, 2005
M.S. in Biology at Northern Michigan University, 2008
Ph.D. in Kinesiology at University of Houston, 2014